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家骆驼主要组织相容性复合体基因组区域的微卫星标记

Microsatellite markers of the major histocompatibility complex genomic region of domestic camels.

作者信息

Knoll Ales, Wijacki Jan, Plasil Martin, Burger Pamela A, Horin Petr

机构信息

Department of Animal Morphology, Physiology and Genetics, Faculty of Agronomy, Mendel University in Brno, Brno, Czechia.

Department of Animal Genetics, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czechia.

出版信息

Front Genet. 2022 Oct 24;13:1015288. doi: 10.3389/fgene.2022.1015288. eCollection 2022.

Abstract

We identified and characterized 11 polymorphic microsatellite markers suitable for routine testing (three in the MHC class I sub-region, four in MHC class II and four in the MHC class III sub-region) of dromedaries and Bactrian camels. In total, 38 dromedaries and 33 Bactrian camels were genotyped, and interspecific differences were observed in the numbers of alleles and in allelic frequencies, as well as in the observed heterozygosity. These loci may be used as markers to study the adaptive genetic diversity of the MHC region in Old World camels.

摘要

我们鉴定并表征了11个适合单峰骆驼和双峰骆驼常规检测的多态微卫星标记(3个位于MHC I类亚区,4个位于MHC II类,4个位于MHC III类亚区)。总共对38只单峰骆驼和33只双峰骆驼进行了基因分型,观察到等位基因数量、等位基因频率以及观察到的杂合度存在种间差异。这些位点可作为研究旧世界骆驼MHC区域适应性遗传多样性的标记。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0fa/9638106/1538c5168de7/fgene-13-1015288-g001.jpg

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