为期6周的普拉提训练联合莳萝补充剂对超重和肥胖女性血清中核仁组织区衍生肽-1、脂质运载蛋白-2浓度及胰岛素抵抗的影响：一项随机对照试验。
Effect of 6 weeks Pilates training along with dill supplementation on serum concentrations of nesfatin-1, lipocalin-2, and insulin resistance in females with overweight and obesity: A randomized controlled trial.
作者信息
Sabzevari Fateme, Mogharnasi Mehdi, Golestani Fateme
机构信息
Department of Exercise Physiology, Faculty of Sport Science, University of Birjand, Birjand, Iran.
出版信息
J Res Med Sci. 2022 Aug 27;27:59. doi: 10.4103/jrms.JRMS_612_20. eCollection 2022.
BACKGROUND
This study aimed to investigate the effect of 6 weeks' pilates training along with dill supplementation on serum concentrations of nesfatin-1, lipocaline-2, and insulin resistance in females with overweight and obesity.
MATERIALS AND METHODS
In this randomized controlled trial study, 45 overweight and obese females are randomly assigned to four groups: Pilates training + dill group (PDG) ( = 12), pilates training + placebo group (PPG) ( = 11), dill supplementation group (DG) ( = 11), and placebo group (PG) ( = 11). Participants of PDG and PPG performed pilates training for 6 weeks (60 min, 3 sessions per week). PDG and DG received dill tablet (three times a day, 6 weeks). Anthropometric measurements, glycemic markers, and blood samples were assessed before (pretest) and after (posttest) 6 weeks of intervention.
RESULTS
Results showed a significant increase in serum concentrations of nesfatin-1 in PDG compared to pretest ( = 0.001). Differences in the serum concentrations of nesfatin-1 in PDG were greater than PPG, DG, and PG ( = 0.01). Furthermore, results found in significant reduction in serum concentrations of lipocalin-2, body mass index (BMI), and waist-hip ratio (WHR) in PDG, PPG, and DG as compared to pretest ( > 0.05). Fasting glucose plasma (FGP) was significantly decreased in all three intervention groups PDG ( < 0.001), PPG ( < 0.001), and DG ( < 0.001) as compared to pretest. Differences in FGP were significantly higher in PDG than PPG, DG, and PG ( = 0.001). A significant reduction was found for insulin only in PDG after 6 weeks of intervention as compared to pretest ( = 0.03). Insulin resistance significantly decreased in PDG ( = 0.03) and PPG ( = 0.04) as compared to pretest. Body fat percent (BFP) was significantly decreased in PDG ( = 0.003), PPG ( = 0.006), and DG ( = 0.01). However, there were no significant inter-group differences in insulin resistance, insulin, serum concentrations of lipocalin-2, BMI, BFP, and WHR after 6 weeks of Pilates training along with dill supplementation ( > 0.05).
CONCLUSION
We concluded that 6 weeks of Pilates training along with dill may be beneficial for improvements in serum concentrations of nesfatin-1 and FGP.
背景
本研究旨在探讨为期6周的普拉提训练以及莳萝补充剂对超重和肥胖女性血清中内脂素-1、lipocalin-2浓度及胰岛素抵抗的影响。
材料与方法
在这项随机对照试验研究中，45名超重和肥胖女性被随机分为四组：普拉提训练+莳萝组（PDG）（n = 12）、普拉提训练+安慰剂组（PPG）（n = 11）、莳萝补充剂组（DG）（n = 11）和安慰剂组（PG）（n = 11）。PDG组和PPG组的参与者进行为期6周的普拉提训练（60分钟，每周3次）。PDG组和DG组服用莳萝片（每日3次，共6周）。在干预6周前（预测试）和干预6周后（后测试）评估人体测量指标、血糖标志物和血样。
结果
结果显示，与预测试相比，PDG组血清内脂素-1浓度显著升高（P = 0.001）。PDG组血清内脂素-1浓度的差异大于PPG组、DG组和PG组（P = 0.01）。此外，结果发现，与预测试相比，PDG组、PPG组和DG组血清lipocalin-2浓度、体重指数（BMI）和腰臀比（WHR）显著降低（P > 0.05）。与预测试相比，所有三个干预组（PDG组（P < 0.001）、PPG组（P < 0.001）和DG组（P < 0.001））的空腹血糖血浆（FGP）均显著降低。PDG组FGP的差异显著高于PPG组、DG组和PG组（P = 0.001）。与预测试相比，干预6周后仅PDG组胰岛素显著降低（P = 0.03）。与预测试相比，PDG组（P = 0.03）和PPG组（P = 0.04）的胰岛素抵抗显著降低。PDG组（P = 0.003）、PPG组（P = 0.006）和DG组（P = 0.01）的体脂百分比（BFP）显著降低。然而，在进行6周的普拉提训练并补充莳萝后，胰岛素抵抗、胰岛素、血清lipocalin-2浓度、BMI、BFP和WHR在组间无显著差异（P > 0.05）。
结论
我们得出结论，为期6周的普拉提训练以及莳萝补充剂可能有助于改善血清内脂素-1浓度和FGP。
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