Golestani Fateme, Mogharnasi Mehdi, Erfani-Far Mahboube, Abtahi-Eivari Seyed Hossein
Department of Exercise Physiology, Faculty of Sport Science, University of Birjand, Birjand, Iran.
Department of Biochemistry, Faculty of Medicine, Gonabad University of Medical Science, Gonabad, Iran.
J Res Med Sci. 2021 Jan 28;26:10. doi: 10.4103/jrms.JRMS_1317_20. eCollection 2021.
We investigated the effects of spirulina under high-intensity interval training (HIIT) on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females.
This is a randomized, quasi-experimental controlled, single-blind with a pre- and post-test design, in which twenty overweight and obese women (body mass index = 29.32 ± 3.01 kg/m, age = 21.55 ± 1.76 years), were randomly divided into the following groups: HIIT + spirulina ( = 10) and HIIT + placebo ( = 10). Running anaerobic sprint test was used for HIIT protocol consisting of six intervals at 35 m maximal speed runs, with a rest of 10 s in each trial (3 times/week, 4 weeks). HIIT + spirulina group received 500 mg of the spirulina pills twice daily for 4 weeks and the second group took placebo.
There was a significant increase in serum levels of nesfatin-1 in HIIT + spirulina ( < 0.0001) but not in HIIT + placebo ( = 0.61) group. Furthermore, results indicated a significant difference between two groups with respect to serum levels of nesfatin-1 ( = 0.04). Serum levels of omentin-1 significantly increased in both groups ( < 0.05). However, there was no significant difference between two groups ( = 0.49). In addition, results showed no significant inter- and intra-group differences in total cholesterol levels, triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol between groups ( > 0.05).
The spirulina under HIIT increased levels of nesfatin-1 and omentin-1 with no effects on the levels of lipid profiles in overweight and obese females.
我们研究了高强度间歇训练（HIIT）期间螺旋藻对超重和肥胖女性中nesfatin-1、网膜素-1水平及血脂谱的影响。
这是一项随机、半实验对照、单盲且有前后测试设计的研究，20名超重和肥胖女性（体重指数=29.32±3.01kg/m²，年龄=21.55±1.76岁）被随机分为以下几组：HIIT+螺旋藻组（n=10）和HIIT+安慰剂组（n=10）。HIIT方案采用跑步无氧冲刺测试，包括以最大速度跑35米的六个间歇，每次间歇休息10秒（每周3次，共4周）。HIIT+螺旋藻组每天服用两次500毫克螺旋藻片，持续4周，第二组服用安慰剂。
HIIT+螺旋藻组血清nesfatin-1水平显著升高（P<0.0001），而HIIT+安慰剂组未升高（P=0.61）。此外，两组血清nesfatin-1水平存在显著差异（P=0.04）。两组网膜素-1血清水平均显著升高（P<0.05）。然而，两组之间无显著差异（P=0.49）。此外，结果显示两组间总胆固醇水平、甘油三酯、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇在组内和组间均无显著差异（P>0.05）。
HIIT期间的螺旋藻可提高超重和肥胖女性的nesfatin-1和网膜素-1水平，对血脂谱水平无影响。
