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罕见病例:下行性坏死性纵隔炎。

A rare case: Descending necrotizing mediastinitis.

作者信息

Ayvaci Barış Murat, Gökdağ Eren

机构信息

Department of Emergency Medicine, Prof. Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Turkey.

Department of Emergency Medicine, School of Medicine, Üsküdar University, İstanbul, Turkey.

出版信息

Turk J Emerg Med. 2022 Sep 30;22(4):230-232. doi: 10.4103/2452-2473.357345. eCollection 2022 Oct-Dec.

DOI:10.4103/2452-2473.357345
PMID:36353386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9639737/
Abstract

Descending necrotizing mediastinitis (DNM) is one of the most critical, and often lethal forms of mediastinitis that develop because of the downward spread of deep neck infections. In this article, we wanted to discuss a case report with DNM secondary to retropharyngeal abscess detected in the emergency department, in accordance with the literature. A 51-year-old male patient presented to the hospital with complaints of fever, sore throat when swallowing, and swelling in the neck. He had no history of any disease, trauma, or surgical intervention. On physical examination of our patient, diffuse hyperemia and edema in the pharyngeal area were detected with swelling, edema, redness, and warmth in the neck, which can be felt on both sides of the trachea with palpation. DNM diagnosis was made by detecting retropharyngeal abscess extending to the mediastinum, mediastinal air images and increased density in adipose tissue with intravenous (IV) contrast-enhanced neck and thorax computed tomography (CT). DNM patients most frequently present with complaints of fever, odynophagia, dyspnea, cervical edema, and pain. The most important clinical finding is edema and hyperemia in the pharynx. Our patient presented to the emergency department with complaints of fever, sore throat when swallowing, and neck swelling, and on physical examination, edema, hyperemia, and temperature increase in the neck region were observed together with hyperemia and edema in the pharyngeal area. Laboratory examinations showed high leukocyte count and C-reactive protein levels. The patient was diagnosed with DNM by performing IV contrast-enhanced cervicothoracic CT imaging and underwent an operation. It should be borne in mind that patients who present to the emergency room with fever, odynophagia, and neck swelling may have a rare but seriously life-threatening DNM.

摘要

下行性坏死性纵隔炎(DNM)是纵隔炎最危急且常致命的一种类型,它是由深部颈部感染向下蔓延所致。在本文中,我们想结合文献讨论一例在急诊科发现的继发于咽后脓肿的DNM病例报告。一名51岁男性患者因发热、吞咽时咽痛及颈部肿胀前来医院就诊。他无任何疾病、外伤或手术干预史。对我们的患者进行体格检查时,发现咽部弥漫性充血和水肿,颈部有肿胀、水肿、发红及发热,气管两侧触诊时均可感觉到。通过静脉注射(IV)对比增强颈部和胸部计算机断层扫描(CT)检测到咽后脓肿延伸至纵隔、纵隔积气影像以及脂肪组织密度增加,从而做出DNM诊断。DNM患者最常出现的症状是发热、吞咽痛、呼吸困难、颈部水肿和疼痛。最重要的临床发现是咽部水肿和充血。我们的患者因发热、吞咽时咽痛及颈部肿胀前来急诊科就诊,体格检查时发现颈部区域水肿、充血及体温升高,同时咽部区域也有充血和水肿。实验室检查显示白细胞计数和C反应蛋白水平升高。通过进行静脉注射对比增强颈胸CT成像,该患者被诊断为DNM并接受了手术。应牢记,因发热、吞咽痛和颈部肿胀前来急诊室的患者可能患有罕见但严重危及生命的DNM。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de08/9639737/ef0c5557666f/TJEM-22-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de08/9639737/ef0c5557666f/TJEM-22-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de08/9639737/ef0c5557666f/TJEM-22-230-g001.jpg

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本文引用的文献

1
Surgical treatment of descending necrotising mediastinitis caused by odontogenic infection: a retrospective analysis of 20 patients.牙源性感染引起的降主动脉坏死性纵隔炎的外科治疗:20 例回顾性分析。
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Diffuse descending necrotizing mediastinitis: surgical therapy and outcome in a single-centre series.弥漫性降主动脉坏死性纵隔炎:单中心系列的手术治疗和结果。
Eur J Cardiothorac Surg. 2012 Oct;42(4):e66-72. doi: 10.1093/ejcts/ezs385. Epub 2012 Jul 3.
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Update on necrotizing mediastinitis: causes, approaches to management, and outcomes.
坏死性纵隔炎更新:病因、治疗方法和预后。
Curr Infect Dis Rep. 2011 Jun;13(3):278-86. doi: 10.1007/s11908-011-0174-z.
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Incidence of and preoperative risk factors for Staphylococcus aureus bacteremia and chest wound infection after cardiac surgery.心脏手术后金黄色葡萄球菌菌血症和胸部伤口感染的发生率及术前危险因素
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Deep neck infection: analysis of 80 cases.颈部深部感染:80例病例分析
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Descending necrotising mediastinitis: a safe treatment algorithm.下行性坏死性纵隔炎:一种安全的治疗方案
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Management of descending necrotizing mediastinitis.降主动脉坏死性纵隔炎的管理
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Laryngoscope. 2004 Apr;114(4):772-5. doi: 10.1097/00005537-200404000-00035.
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