Centre for Osteoarthritis Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK.
Methods Mol Biol. 2023;2598:357-373. doi: 10.1007/978-1-0716-2839-3_26.
In this chapter, we describe an induced model of osteoarthritis in mice, frequently employed in the study of this disease. We outline in detail the surgical induction of disease and preparation of samples for histological assessment of disease.
在本章中，我们描述了一种在小鼠中诱导骨关节炎的模型，该模型常用于研究这种疾病。我们详细描述了疾病的手术诱导和用于组织学评估疾病的样本制备。
