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印度抗菌药物耐药性环境层面的现有政策/指南:通过综述和SWOT分析洞察关键方面

Existing Policies/Guidelines on the Environmental Dimension of Antimicrobial Resistance in India: An Insight into the Key Facets through Review and SWOT Analysis.

作者信息

Debnath Falguni, Chakraborty Debjit, Giri Sandip, Saha Shatabdi, Pyne Soume, Chakraverty Raja, Majumdar Agniva, Deb Alok Kumar, Diwan Vishal, Bhatia Rajesh, Dutta Shanta

机构信息

Indian Council of Medical Research (ICMR), National Institute of Cholera & Enteric Diseases, Kolkata 700010, India.

Indian Council of Medical Research (ICMR), National Institute for Research in Environmental Health, Bhopal 462030, India.

出版信息

Trop Med Infect Dis. 2022 Oct 29;7(11):336. doi: 10.3390/tropicalmed7110336.

Abstract

BACKGROUND

Antimicrobial resistance (AMR) is a multidimensional phenomenon. The environment acts as a mixing pot of drug-resistant bacteria from many sources such as pharmaceutical, biomedical, veterinary, and agricultural sectors. In this study, we analysed the existing AMR-related policies/guidelines/legislations in India in the above domains and how the current practices are being guided by them.

METHODS

We used a convergent parallel mix method design. Quantitative data were collected through a review of policies/guidelines/legislations in the said domains and analysed using the SWOT tool parallelly supported by key informant interviews of domain-specific stakeholders.

RESULTS

Altogether, 19 existing AMR policies/guidelines/legislations were identified. The existence of few policies/guidelines in each domain indicated the evolving environment for policy interventions. However, the lack of capacity among farmers, inadequate provision for structured capacity building, high cost of alternatives to antimicrobials, and lack of provision of incentivisation in case of crop failure were identified as the major weaknesses prevalent across the domains. Opportunities for policy refinements/the introduction of new policies are ample. However, easy access to antimicrobials and injudicious use imposes threats to AMR containment in all sectors.

CONCLUSIONS

Despite having a few policies for the containment of AMR, their implementation witnesses challenge due to the lack of collaborative approaches, the existence of policies disjointed from ground reality, infrastructural issues, and the lack of capacity and resources.

摘要

背景

抗菌药物耐药性(AMR)是一个多维度的现象。环境充当了来自制药、生物医学、兽医和农业等多个领域的耐药菌的混合池。在本研究中,我们分析了印度在上述领域现有的与AMR相关的政策/指南/法规,以及当前的实践是如何受到它们的指导的。

方法

我们采用了一种融合平行混合方法设计。通过审查上述领域的政策/指南/法规收集定量数据,并使用SWOT工具进行分析,同时得到特定领域利益相关者的关键信息访谈的支持。

结果

总共确定了19项现有的AMR政策/指南/法规。每个领域中政策/指南数量较少表明了政策干预的不断变化的环境。然而,农民能力不足、缺乏结构化能力建设的规定、抗菌药物替代品成本高以及作物歉收时缺乏激励措施被确定为各领域普遍存在的主要弱点。政策完善/引入新政策的机会很多。然而,抗菌药物的容易获取和不合理使用对所有部门的AMR控制构成了威胁。

结论

尽管有一些控制AMR的政策,但其实施面临挑战,原因包括缺乏协作方法、存在与实际情况脱节的政策、基础设施问题以及缺乏能力和资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cde/9699572/6048cf74ccd2/tropicalmed-07-00336-g001.jpg

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