Sri Anna, Bailey Kirsten E, Gilkerson James R, Browning Glenn F, Hardefeldt Laura Y
Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, VIC 3010, Australia.
National Centre for Antimicrobial Stewardship, Peter Doherty Institute, Parkville, VIC 3052, Australia.
Antibiotics (Basel). 2022 Nov 10;11(11):1589. doi: 10.3390/antibiotics11111589.
The timely implementation of antimicrobial stewardship interventions could delay or prevent the development of higher levels of antimicrobial resistance in the future. In food-producing animals in Australia, high-importance antimicrobials, as rated by the Australian Strategic and Technical Advisory Group (ASTAG), include virginiamycin and third-generation cephalosporins (in individual pigs or cattle). The use of high-importance antimicrobials in companion animals is more widespread and less regulated. There is no national antimicrobial use surveillance system for animals in Australia. Consequently, there is a gap in the knowledge about reasonable use across all sectors of veterinary practice. This study explored attitudes towards the use in veterinary medicine of antimicrobials with high importance to human health, and determined levels of agreement about the introduction of restrictions or other conditions on this use. An online survey was distributed via social media and email from June to December 2020 to veterinarians working in Australia. Of the 278 respondents working in clinical practice, 49% had heard of the ASTAG rating system, and 22% used a traffic light system for antimicrobial importance in their practice. Overall, 61% of participants disagreed that veterinarians should be able to prescribe high-importance antimicrobials without restrictions. If there were to be restrictions, there was most agreement amongst all respondents for only restricting high-importance antimicrobials (73%). There is a need for education, guidance, and practical support for veterinarians for prescribing high-importance antimicrobials alongside any restrictions.
及时实施抗菌药物管理干预措施可以延缓或预防未来更高水平的抗菌药物耐药性的出现。在澳大利亚的食用动物中，澳大利亚战略和技术咨询小组（ASTAG）评定的高重要性抗菌药物包括维吉尼亚霉素和第三代头孢菌素（用于个别猪或牛）。高重要性抗菌药物在伴侣动物中的使用更为广泛且监管较少。澳大利亚没有针对动物的全国抗菌药物使用监测系统。因此，在兽医实践的所有领域，关于合理使用抗菌药物的知识存在空白。本研究探讨了对兽医使用对人类健康具有高重要性的抗菌药物的态度，并确定了在对此类使用实施限制或其他条件方面的共识程度。2020年6月至12月，通过社交媒体和电子邮件向在澳大利亚工作的兽医发放了一项在线调查问卷。在278名从事临床实践的受访者中，49%听说过ASTAG评级系统，22%在其实践中使用抗菌药物重要性的交通灯系统。总体而言，61%的参与者不同意兽医应能够不受限制地开具高重要性抗菌药物。如果要实施限制，所有受访者中大多数同意仅限制高重要性抗菌药物（73%）。在实施任何限制的同时，需要为兽医提供关于开具高重要性抗菌药物的教育、指导和实际支持。
