Emergency Department, Rouen University Hospital, 76031 Rouen, France.
Laboratory "Research on Healthcare Performance" (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1, 69008 Lyon, France.
Int J Environ Res Public Health. 2022 Oct 28;19(21):14044. doi: 10.3390/ijerph192114044.
Medication, antibiotics, and immunization are three major and cost-effective medical interventions but their use is balanced. Knowledge, attitudes and practices (KAP) are a cornerstone. This retrospective study aims at analyzing KAP related to these concerns among the public service population in order to establish the basis for the implementation of selective preventive actions. From a cross-sectional anonymous online questionnaire-based survey among the insurees of a French mutual organization (, UROPS), 33 questions related to medication, antibiotics and vaccination were extracted to evaluate KAP. New variables were constituted: levels of knowledge, antibiotic misuse, proactive behavior and vaccinophobia. Multiple correspondence analysis was performed to identify respondents' homogenous groups. In addition, bivariate statistical comparisons were provided and logistic regressions were carried out to identify determinants of these new variables. Public service population (workers and retired) were highly exposed to polymedication (8.7% vs. 24.4%, < 0.0001), hypnotics overtake (24.3% vs. 18.4%, < 0.0001), and misuse antibiotics (33.2% vs. 22.6%, < 0.0001) despite good levels of knowledge. Proportions of vaccinophobia was low (0.8% vs. 1.7%, < 0.0001). However, workers have different KAP than retired, without shared determinants in the 3 health domains studied. Respondents were proactive (85.8% vs. 81.6%, < 0.0001), used multiple sources of trustworthy information and seems to be ready for the delegation of health tasks. Thus, preventive actions related to antibiotics and polymedication should be a priority in vaccination education for mutual organizations such as UROPS. Studying their insurees longitudinally could be interesting to highlight the impact of selective prevention on behaviors, through trusted health professionals (general practitioners, pharmacists…).
药物治疗、抗生素和免疫接种是三大具有成本效益的医疗干预措施，但它们的使用需要平衡。知识、态度和实践（KAP）是一个基石。本回顾性研究旨在分析公众服务人群中与这些问题相关的 KAP，为实施有针对性的预防措施奠定基础。通过对法国互助组织（UROPS）的参保人进行横断面匿名在线问卷调查，共提取了 33 个与药物治疗、抗生素和疫苗接种相关的问题，以评估 KAP。新变量包括知识水平、抗生素滥用、主动行为和疫苗恐惧症。采用多元对应分析（MCA）来识别受访者的同质群体。此外，还提供了双变量统计比较，并进行了逻辑回归分析，以确定这些新变量的决定因素。公共服务人群（工人和退休人员）普遍存在多药治疗（8.7%比 24.4%， < 0.0001）、催眠药替代（24.3%比 18.4%， < 0.0001）和抗生素滥用（33.2%比 22.6%， < 0.0001）的情况，尽管他们的知识水平良好。疫苗恐惧症的比例较低（0.8%比 1.7%， < 0.0001）。然而，工人和退休人员在 3 个研究领域的 KAP 不同，没有共同的决定因素。受访者具有主动性（85.8%比 81.6%， < 0.0001），使用了多种值得信赖的信息来源，并且似乎准备好将健康任务委托给他人。因此，互助组织（如 UROPS）在疫苗接种教育中，应优先考虑与抗生素和多药治疗相关的预防措施。对参保人进行纵向研究可能会很有趣，可以通过值得信赖的卫生专业人员（全科医生、药剂师等）来突出有针对性的预防措施对行为的影响。
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