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胆道闭锁初始治疗的手术与医学方面:立场文件。

Surgical and Medical Aspects of the Initial Treatment of Biliary Atresia: Position Paper.

作者信息

Davenport Mark, Madadi-Sanjani Omid, Chardot Christophe, Verkade Henkjan J, Karpen Saul J, Petersen Claus

机构信息

Department of Paediatric Surgery, Kings College Hospital, London SE5 9RS, UK.

Klinik für Kinderchirurgie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

出版信息

J Clin Med. 2022 Nov 7;11(21):6601. doi: 10.3390/jcm11216601.

Abstract

Biliary atresia, a fibro-obliterative disease of the newborn, is usually initially treated by Kasai portoenterostomy, although there are many variations in technique and different options for post-operative adjuvant medical therapy. A questionnaire on such topics (e.g., open vs. laparoscopic; the need for liver mobilisation; use of post-operative steroids; use of post-operative anti-viral therapy, etc.) was circulated to delegates ( = 43) of an international webinar (Biliary Atresia and Related Diseases-BARD) held in June 2021. Respondents were mostly European, but included some from North America, and represented 18 different countries overall. The results of this survey are presented here, together with a commentary and review from an expert panel convened for the meeting on current trends in practice.

摘要

胆道闭锁是一种新生儿的纤维闭塞性疾病,通常最初通过Kasai肝门肠吻合术进行治疗,尽管该技术存在许多变体,术后辅助药物治疗也有不同选择。一份关于此类主题(例如,开放手术与腹腔镜手术;肝脏游离的必要性;术后使用类固醇;术后使用抗病毒治疗等)的问卷被分发给了2021年6月举行的一次国际网络研讨会(胆道闭锁及相关疾病-BARD)的与会代表(共43人)。受访者大多来自欧洲,但也包括一些来自北美的人,总共代表18个不同的国家。本文展示了这项调查的结果,以及为该会议召集的一个专家小组对当前实践趋势的评论和综述。

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