Zemková Mária, Minárik Peter, Jablonská Eva, Veselý Jozef, Bohlen Jan, Kubásek Jiří, Lipov Jan, Ruml Tomáš, Havlas Vojtěch, Král Robert
Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 121 16 Praha, Czech Republic.
Research Centre, University of Žilina, Univerzitná 8215/1, 01026 Žilina, Slovakia.
Materials (Basel). 2022 Oct 28;15(21):7571. doi: 10.3390/ma15217571.
In the field of magnesium-based degradable implantable devices, the Mg-Y-RE-Zr alloying system (WE-type) has gained popularity due to its satisfying degradation rate together with mechanical strength. However, utilization of RE and Zr in the WE-type alloys was originally driven to improve Mg-based alloys for high-temperature applications in the industry, while for medical purposes, there is a question of whether the amount of alloying elements may be further optimized. For this reason, our paper presents the Mg-3Y (W3) magnesium alloy as an alternative to the WE43 alloy. This study shows that the omission of RE and Zr elements did not compromise the corrosion resistance and the degradation rate of the W3 alloy when compared with the WE43 alloy; appropriate biocompatibility was preserved as well. It was shown that the decrease in the mechanical strength caused by the omission of RE and Zr from the WE43 alloy could be compensated for by severe plastic deformation, as achieved in this study, by equal channel angular pressing. Ultrafine-grained W3 alloy exhibited compression yield strength of 362 ± 6 MPa and plastic deformation at maximum stress of 18 ± 1%. Overall, the early results of this study put forward the motion of avoiding RE elements and Zr in magnesium alloy as a suitable material for biodegradable applications and showed that solo alloying of yttrium is sufficient for maintaining desirable properties of the material at once.
在镁基可降解植入式器件领域,Mg-Y-RE-Zr合金体系(WE型)因其令人满意的降解速率和机械强度而受到欢迎。然而,WE型合金中稀土元素(RE)和锆(Zr)的使用最初是为了改进镁基合金以用于工业高温应用,而对于医疗用途而言,合金元素的用量是否可以进一步优化仍是个问题。因此,我们的论文提出了Mg-3Y(W3)镁合金作为WE43合金的替代品。这项研究表明,与WE43合金相比,省略RE和Zr元素不会损害W3合金的耐腐蚀性和降解速率;同时也保留了适当的生物相容性。研究表明,通过本研究中采用的等通道转角挤压进行严重塑性变形,可以弥补因从WE43合金中省略RE和Zr而导致的机械强度下降。超细晶粒W3合金的压缩屈服强度为362±6MPa,最大应力下的塑性变形为18±1%。总体而言,这项研究的早期结果提出了在镁合金中避免使用RE元素和Zr作为可生物降解应用合适材料的提议,并表明单独添加钇就足以同时保持材料的理想性能。