Li Linqiao, Ma Yuan, Li Wei, Tang Guorong, Jiang Yan, Li Huangcui, Jiang Shuxiang, Zhou Yun, Yang Yuan, Zhang Ting, Yang Weizhong, Ma Libing, Feng Luzhao
Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin 541001, China.
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Vaccines (Basel). 2022 Nov 10;10(11):1897. doi: 10.3390/vaccines10111897.
To determine the vaccine hesitancy of pneumococcal conjugate vaccines (PCVs) in a low-resource setting in China and to identify associated factors, a face-to-face questionnaire survey was conducted in the city of Guilin, China, from December 2021 to March 2022, which comprised sociodemographic information, attitudes toward vaccines and pneumonia, and PCV13 vaccination willingness and willingness to pay (WTP). Stepwise logistic regression and Tobit regression models were fitted to identify factors associated with PCV13 vaccination willingness and WTP, respectively. In total, 1254 questionnaires were included, of which 899, 254, and 101 participants showed acceptance, hesitancy, and refusal to vaccinate their children with PCV13, respectively. Only 39.07% of participants knew about PCV13 before this survey. A total of 558 (48.40%) participants accepted the full payment of vaccination, and 477 (41.37%) other participants accepted the partial payment, with a median cost of CNY 920.00. Demographics, social and psychological context, and attitudes toward vaccines were all associated with PCV13 vaccination but varied for hesitators and refusers. There is a substantial local demand for vaccinating children with PCV13 and partial payment is widely accepted. More publicity and educational efforts and a socially supportive environment are required to alleviate vaccine hesitancy.
为了确定中国资源匮乏地区肺炎球菌结合疫苗（PCV）的疫苗犹豫情况并识别相关因素，于2021年12月至2022年3月在中国桂林市开展了一项面对面问卷调查，内容包括社会人口统计学信息、对疫苗和肺炎的态度、PCV13疫苗接种意愿及支付意愿（WTP）。分别采用逐步逻辑回归和Tobit回归模型来识别与PCV13疫苗接种意愿及支付意愿相关的因素。总共纳入了1254份问卷，其中899名、254名和101名参与者分别表示接受、犹豫和拒绝为其子女接种PCV13疫苗。在本次调查之前，只有39.07%的参与者了解PCV13疫苗。共有558名（48.40%）参与者接受全额疫苗接种费用，477名（41.37%）其他参与者接受部分费用，中位数费用为920.00元人民币。人口统计学、社会和心理背景以及对疫苗的态度均与PCV13疫苗接种相关，但对于犹豫者和拒绝者有所不同。当地对为儿童接种PCV13疫苗有很大需求，并且部分费用支付被广泛接受。需要更多的宣传教育努力和社会支持环境来缓解疫苗犹豫情况。
