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SARS-CoV-2 在人类-动物界面:从非洲角度看对全球公共卫生的影响。

SARS-CoV-2 at the Human-Animal Interface: Implication for Global Public Health from an African Perspective.

机构信息

National Veterinary Research Institute, Vom 930001, Nigeria.

Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

出版信息

Viruses. 2022 Nov 9;14(11):2473. doi: 10.3390/v14112473.

DOI:10.3390/v14112473
PMID:36366571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9696393/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic has become the most far-reaching public health crisis of modern times. Several efforts are underway to unravel its root cause as well as to proffer adequate preventive or inhibitive measures. Zoonotic spillover of the causative virus from an animal reservoir to the human population is being studied as the most likely event leading to the pandemic. Consequently, it is important to consider viral evolution and the process of spread within zoonotic anthropogenic transmission cycles as a global public health impact. The diverse routes of interspecies transmission of SARS-CoV-2 offer great potential for a future reservoir of pandemic viruses evolving from the current SARS-CoV-2 pandemic circulation. To mitigate possible future infectious disease outbreaks in Africa and elsewhere, there is an urgent need for adequate global surveillance, prevention, and control measures that must include a focus on known and novel emerging zoonotic pathogens through a one health approach. Human immunization efforts should be approached equally through the transfer of cutting-edge technology for vaccine manufacturing throughout the world to ensure global public health and one health.

摘要

2019 年冠状病毒病(COVID-19)大流行已成为现代史上影响范围最广的公共卫生危机。目前正在进行多项努力,以揭示其根本原因,并提供充分的预防或抑制措施。从动物宿主向人类传播的致病病毒的人畜共患病溢出被认为是导致大流行的最可能事件。因此,重要的是要考虑病毒进化以及人畜共患病人为传播周期内的传播过程,因为这对全球公共卫生有重大影响。SARS-CoV-2 的多种种间传播途径为当前 SARS-CoV-2 大流行循环中可能进化出的未来大流行病毒提供了巨大的潜力。为了减轻非洲和其他地区未来可能发生的传染病暴发,迫切需要采取充分的全球监测、预防和控制措施,这些措施必须通过“同一健康”方法关注已知和新型新兴人畜共患病病原体。应通过向世界各地转让疫苗制造的尖端技术,平等地开展人类免疫工作,以确保全球公共卫生和同一健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3310/9696393/42207f34b154/viruses-14-02473-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3310/9696393/679e629ac681/viruses-14-02473-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3310/9696393/42207f34b154/viruses-14-02473-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3310/9696393/679e629ac681/viruses-14-02473-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3310/9696393/42207f34b154/viruses-14-02473-g002.jpg

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