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一种来自构巢曲霉的异羟肟酸,对变形杆菌属具有抗菌活性。

A hydroxamic acid from Aspergillus nidulans with antibiotic activity against Proteus species.

作者信息

Middleton A J, Cole D S, Macdonald K D

出版信息

J Antibiot (Tokyo). 1978 Nov;31(11):1110-5. doi: 10.7164/antibiotics.31.1110.

DOI:10.7164/antibiotics.31.1110
PMID:363670
Abstract

An iron-complexing antibiotic with a narrow spectrum of biological activity was produced by several strains of Aspergillus nidulans when grown in a low-iron, chemically defined medium. Its chemical and biological properties closely resembled those of desferritriacetylfusigen, a metabolite of several other Aspergilli and Penicillia.

摘要

几种构巢曲霉在低铁的化学成分确定的培养基中生长时,产生了一种具有窄生物活性谱的铁络合抗生素。其化学和生物学特性与去铁三乙酰真菌铁载体(其他几种曲霉和青霉的一种代谢产物)的特性极为相似。

相似文献

1
A hydroxamic acid from Aspergillus nidulans with antibiotic activity against Proteus species.一种来自构巢曲霉的异羟肟酸,对变形杆菌属具有抗菌活性。
J Antibiot (Tokyo). 1978 Nov;31(11):1110-5. doi: 10.7164/antibiotics.31.1110.
2
Extracellular siderophores of rapidly growing Aspergillus nidulans and Penicillium chrysogenum.快速生长的构巢曲霉和产黄青霉的细胞外铁载体
J Bacteriol. 1982 May;150(2):785-7. doi: 10.1128/jb.150.2.785-787.1982.
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Cellular and extracellular siderophores of Aspergillus nidulans and Penicillium chrysogenum.构巢曲霉和产黄青霉的细胞内和细胞外铁载体
Mol Cell Biol. 1981 Feb;1(2):94-100. doi: 10.1128/mcb.1.2.94-100.1981.
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Aspergillic acids produced by mixed cultures of Aspergillus flavus and Aspergillus nidulans.由黄曲霉和构巢曲霉混合培养产生的曲霉酸。
J Gen Microbiol. 1984 Feb;130(2):319-23. doi: 10.1099/00221287-130-2-319.
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[Metabolites of microorganisms. 143. Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components].
Helv Chim Acta. 1974;57(8):2459-77. doi: 10.1002/hlca.19740570818.
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Rhodotorulic acid, a diketopiperazine dihydroxamic acid with growth-factor activity. I. Isolation and characterization.红酵母氨酸,一种具有生长因子活性的二酮哌嗪二异羟肟酸。I. 分离与特性鉴定。
Biochemistry. 1968 Oct;7(10):3734-9. doi: 10.1021/bi00850a054.
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Hydroxamic acids in nature.自然界中的异羟肟酸。
Science. 1967 Jun 16;156(3781):1443-7. doi: 10.1126/science.156.3781.1443.
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Metabolic products of microoorganisms. 163. Desferritriacetylfusigen, an antibiotic from Aspergillus deflectus.微生物的代谢产物。163. 去铁三乙酰融合素,一种来自偏肿曲霉的抗生素。
J Antibiot (Tokyo). 1977 Feb;30(2):125-8. doi: 10.7164/antibiotics.30.125.
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Interaction between acetohydroxamic acid and 12 antibiotics against 14 gram-negative pathogenic bacteria.乙酰氧肟酸与12种抗生素对14种革兰氏阴性病原菌的相互作用。
Antimicrob Agents Chemother. 1974 Feb;5(2):106-10. doi: 10.1128/AAC.5.2.106.
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Structures of the naturally occurring hydroxamic acids, fusarinines A and B.天然存在的异羟肟酸(镰刀菌素A和B)的结构。
Biochemistry. 1968 Jan;7(1):184-90. doi: 10.1021/bi00841a023.

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