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氢化可的松引起的症状性窦性心动过缓。

Hydrocortisone-induced symptomatic sinus bradycardia.

机构信息

Department of Cardiology, Betsi Cadwaladr University Health Board, Wrexham, Gwynedd, UK.

Department of Cardiology, Betsi Cadwaladr University Health Board, Wrexham, Gwynedd, UK

出版信息

BMJ Case Rep. 2022 Nov 14;15(11):e252878. doi: 10.1136/bcr-2022-252878.

Abstract

Steroids are commonly prescribed medications that have a wide range of adverse effects. Bradycardia is one of the rare but significant side effects of steroid use, and only a few cases have been reported with bradycardia as a side effect. In this report, we present a case of a woman in her early 50s who developed severe symptomatic sinus bradycardia following high-dose administration of intravenous hydrocortisone, initiated for acute exacerbation of Crohn's disease. Her symptoms entirely resolved after discontinuation of the steroid. This case highlights the importance of obtaining baseline ECG and cardiac monitoring in patients treated with pulsed high-dose steroids.

摘要

类固醇是常用的处方药物,具有广泛的不良反应。心动过缓是类固醇使用的罕见但重要的副作用之一,仅有少数病例报道过以心动过缓为副作用。在本报告中,我们介绍了一位 50 岁出头的女性病例,她在因克罗恩病急性加重而接受静脉注射氢化可的松大剂量冲击治疗后出现严重症状性窦性心动过缓。停用类固醇后,她的症状完全缓解。本病例强调了在接受脉冲大剂量类固醇治疗的患者中获取基线心电图和心脏监测的重要性。

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