Nie Ai-Qin, Chen Xiao-Min, Li Qiang
Department of Ophthalmology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
BMC Ophthalmol. 2022 Nov 16;22(1):442. doi: 10.1186/s12886-022-02654-x.
Herpes simplex keratitis (HSK) is a rare and sight-threatening complication following refractive surgery. SmartSurf surgery is the result of combining transepithelial photorefractive keratectomy (trans-PRK) with Smart Pulse Technology (SPT) to diminish surface irregularities of the residual stromal bed after surgery with less pain, faster re-epithelialization, and better postoperative visual acuity. In this article, we report the first case of HSK following SmartSurf without history of herpetic eye disease.
A 21-year-old woman underwent bilateral SmartSurf without history of clinical herpetic infection, active eye disease, or systemic disease. Mild superficial punctate keratitis occurred on the tenth postoperative day. The condition was not improved by ophthalmic drugs of anti-inflammation or epithelial healings. Dendritic corneal ulcer appeared within one month, which is the commonly recognized clinical manifestation of herpes simplex keratitis. The patient was managed with topical and systemic antiviral agents. After nine days of antiviral therapy, the lesion healed up, remaining mild stromal scarring in both eyes ultimately.
Herpes simplex keratitis is a rare but sight-threatening complication following refractive surgery. For the ocular irritation symptoms of postoperative patients, we should consider the possibility of HSK and give timely treatment.
单纯疱疹性角膜炎(HSK)是屈光手术后一种罕见且威胁视力的并发症。SmartSurf手术是将经上皮准分子原位角膜磨镶术(trans-PRK)与智能脉冲技术(SPT)相结合的成果,旨在减少手术后残余基质床的表面不规则性,减轻疼痛,加快上皮愈合,并提高术后视力。在本文中,我们报告了首例无疱疹性眼病病史的SmartSurf手术后发生HSK的病例。
一名21岁女性在无临床疱疹感染、活动性眼病或全身性疾病病史的情况下接受了双侧SmartSurf手术。术后第10天出现轻度浅层点状角膜炎。使用抗炎或促进上皮愈合的眼科药物治疗后病情未改善。1个月内出现树枝状角膜溃疡,这是单纯疱疹性角膜炎公认的临床表现。患者接受了局部和全身抗病毒药物治疗。抗病毒治疗9天后,病变愈合,最终双眼均遗留轻度基质瘢痕。
单纯疱疹性角膜炎是屈光手术后一种罕见但威胁视力的并发症。对于术后患者出现的眼部刺激症状,应考虑HSK的可能性并及时给予治疗。