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白内障手术后患者出现类似单纯疱疹性角膜炎的上皮性角膜炎:一例报告。

Epithelial keratitis mimicking herpes simplex keratitis in a patient after cataract surgery: A case report.

作者信息

Zou Ming, Zhang Yi, Huang Xi, Gao Sheng, Liu Chunling

机构信息

Department of Ophthalmology, West China Hospital of Sichuan University, ChengDu, Sichuan, China.

出版信息

Medicine (Baltimore). 2019 Jul;98(30):e16591. doi: 10.1097/MD.0000000000016591.

Abstract

RATIONALE

Epithelial keratitis is a common complication after cataract surgery. Many factors have been attributed to this clinical phenomenon.

PATIENT CONCERNS

An 82-year-old woman without previous herpes simplex keratitis (HSK) underwent an uncomplicated clear corneal phacoemulsification procedure in the right eye. In the late postoperative period, epithelial keratitis developed in this same eye.

DIAGNOSIS

An initial diagnosis of HSK was made clinically. The lesion was refractory to antiviral treatment and had progressed. After topical acyclovir cessation and vigorous lubrication, a diagnosis of toxic keratitis was finally made.

OUTCOMES

The corneal epithelial defect and dendritic lesion presented initially. Responding to antiviral treatment, this corneal lesion aggravated and revealed large epithelial erosion. After topical acyclovir cessation and initiation of vigorous lubrication, the toxic keratitis was completely resolved.

LESSONS

Epithelial keratitis following cataract surgery is a common complication and can be misdiagnosed early in its disease course. Physicians should be alert to the possibility of HSK. Polymerase chain reaction detection is helpful in diagnosing this disease.

摘要

原理

上皮性角膜炎是白内障手术后的常见并发症。许多因素被认为与这一临床现象有关。

患者情况

一名82岁女性,既往无单纯疱疹性角膜炎(HSK),右眼行无并发症的透明角膜超声乳化手术。术后晚期,该眼发生上皮性角膜炎。

诊断

临床初步诊断为HSK。病变对抗病毒治疗无效且病情进展。停用局部阿昔洛韦并积极润滑后,最终诊断为中毒性角膜炎。

结果

最初出现角膜上皮缺损和树枝状病变。对抗病毒治疗有反应,但角膜病变加重,出现大面积上皮糜烂。停用局部阿昔洛韦并开始积极润滑后,中毒性角膜炎完全消退。

经验教训

白内障手术后的上皮性角膜炎是常见并发症,在病程早期可能被误诊。医生应警惕HSK的可能性。聚合酶链反应检测有助于诊断该病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f4a/6708949/71c67f9d0d1e/medi-98-e16591-g001.jpg

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