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皮肤过敏性疾病患者和免疫治疗患者的SARS-CoV-2疫苗接种循证指南。

Evidence-Based Guidelines for SARS-COV-2 Vaccination of Patients of Skin Allergic Diseases and Patients on Immuno-Therapeutics.

作者信息

Das Anupam, De Abhishek, Godse Kiran, Sangolli Prabhakar, Zawar Vijay, Sharma Nidhi, Girdhar Mukesh, Podder Indrashis, Shah Bela, Dhar Sandipan

机构信息

Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Department of Dermatology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.

出版信息

Indian J Dermatol. 2022 May-Jun;67(3):314. doi: 10.4103/ijd.ijd_440_21.

Abstract

There is a dearth of data regarding the safety and timing of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) vaccination of patients on immunosuppressive or immunomodulatory therapies. However, data from other vaccine trials may be extrapolated to get an idea regarding the recommendation of SARS-COV-2 vaccines. All the novel SARS-COV-2 vaccines are non-live, thus ensuring the safety of the vaccines. However, the vaccines may not be able to generate an equipotent immunogenic response in patients receiving immunotherapeutics, in comparison to those who are not. We have attempted to put forward certain statements, with respect to SARS-COV-2 vaccination of patients who are on treatment for different dermatological conditions. However, the risk-benefit ratio must be discussed between the patient and the physician, and the final call should be individualized.

摘要

关于接受免疫抑制或免疫调节治疗的患者接种严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫苗的安全性和时机,数据匮乏。然而,其他疫苗试验的数据可用于推断有关SARS-CoV-2疫苗接种建议的情况。所有新型SARS-CoV-2疫苗均为非活性疫苗,因此可确保疫苗的安全性。然而,与未接受免疫治疗的患者相比,这些疫苗在接受免疫治疗的患者中可能无法产生同等效力的免疫原性反应。我们试图就患有不同皮肤病的患者接种SARS-CoV-2疫苗提出某些声明。然而,患者和医生必须讨论风险效益比,最终决定应因人而异。

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