Wen Yanting, Guo Dan, Zhang Jing, Liu Xiaotian, Liu Ting, Li Lu, Jiang Shixie, Wu Dan, Jiang Huabei
Department of Ultrasound Imaging, The Fifth People's Hospital of Chengdu, Chengdu, China.
School of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing, China.
Front Physiol. 2022 Oct 19;13:1036621. doi: 10.3389/fphys.2022.1036621. eCollection 2022.
Photoacoustic tomography (PAT) is an emerging biomedical imaging modality that combines optical and ultrasonic imaging, providing overlapping fields of view. This hybrid approach allows for a natural integration of PAT and ultrasound (US) imaging in a single platform. Due to the similarities in signal acquisition and processing, the combination of PAT and US imaging creates a new hybrid imaging for novel clinical applications. Over the recent years, particular attention is paid to the development of PAT/US dual-modal systems highlighting mutual benefits in clinical cases, with an aim of substantially improving the specificity and sensitivity for diagnosis of diseases. The demonstrated feasibility and accuracy in these efforts open an avenue of translating PAT/US imaging to practical clinical applications. In this review, the current PAT/US dual-modal imaging systems are discussed in detail, and their promising clinical applications are presented and compared systematically. Finally, this review describes the potential impacts of these combined systems in the coming future.
光声断层扫描（PAT）是一种新兴的生物医学成像模式，它将光学成像和超声成像相结合，提供重叠的视野。这种混合方法允许在单个平台上自然地集成PAT和超声（US）成像。由于信号采集和处理方面的相似性，PAT和US成像的结合为新型临床应用创造了一种新的混合成像。近年来，人们特别关注PAT/US双模态系统的开发，突出了其在临床病例中的互利之处，目的是大幅提高疾病诊断的特异性和敏感性。这些努力中所展示的可行性和准确性为将PAT/US成像转化为实际临床应用开辟了一条途径。在这篇综述中，详细讨论了当前的PAT/US双模态成像系统，并系统地介绍和比较了它们有前景的临床应用。最后，这篇综述描述了这些组合系统在未来可能产生的影响。
