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中风健康管理:预防复发性缺血性中风的新策略。

Stroke health management: Novel strategies for the prevention of recurrent ischemic stroke.

作者信息

Jiang Lili, Zhou Yu, Zhang Li, Wu Lingling, Shi Haibin, He Bin, Wang Yao, Liu Qianghui, Ji Xueli, Zhang Xintong, Jiang Lei, Sun Hao

机构信息

Department of Emergency, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Department of Interventional Radiography, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China.

出版信息

Front Neurol. 2022 Oct 26;13:1018794. doi: 10.3389/fneur.2022.1018794. eCollection 2022.

Abstract

OBJECTIVES

The aim of the study was to assess the effect of the stroke health management model on the prognosis and recurrence of mild to moderate ischemic stroke, guided by the stroke health manager based on the patients' needs. In addition, up-to-date evidence of healthcare resource allocation, planning, and optimization is provided.

METHODS

The current research was a retrospective, observational, single-center, history-controlled study with patients divided into two groups, namely, the intervention group and the control group, following the guidance of the stroke health manager. The control group patients received standard medical care during hospitalization, which consisted of advice on healthy lifestyle choices carried out by the bed nurse, but no structured education, WeChat group, or clinical consultation was included. The intervention group patients, in addition to the standard medical care, received health management and health education from the stroke health manager, and after hospital discharge, the patients were followed up over the telephone by the health manager to see if there was any recurrence or readmission.

RESULTS

From 1 January 2018 to 31 December 2020, 382 patients with acute ischemic stroke were enrolled in this study. Through the univariate regression analysis, we found that SHM intervention was associated with a significantly lower risk of recurrence (HR = 0.459). We constructed a nomogram based on the significant variables from the regression analysis and also analyzed the association between the control group and the SHM intervention group among all subgroups using the Cox proportional hazards model to assess the effect of the stroke health management model. Most patients in this study had a total risk point between 170 and 270. The C-index value was 0.76, and the time-dependent AUC for predicting recurrence was >0.7.

CONCLUSION

The stroke health manager-guided management model based on patients' needs can better control the risk factors of stroke and significantly reduce the recurrence rate of mild to moderate ischemic stroke within 1 year.

摘要

目的

本研究旨在评估在卒中健康管理师根据患者需求进行指导下,卒中健康管理模式对轻至中度缺血性卒中预后及复发的影响。此外,还提供了医疗资源分配、规划和优化的最新证据。

方法

本研究为回顾性、观察性、单中心、历史对照研究,在卒中健康管理师的指导下,将患者分为两组,即干预组和对照组。对照组患者在住院期间接受标准医疗护理,包括床位护士提供的健康生活方式选择建议,但不包括结构化教育、微信群或临床咨询。干预组患者除接受标准医疗护理外,还接受卒中健康管理师的健康管理和健康教育,出院后,健康管理师通过电话对患者进行随访,观察是否有复发或再次入院情况。

结果

2018年1月1日至2020年12月31日,本研究共纳入382例急性缺血性卒中患者。通过单因素回归分析,我们发现SHM干预与显著降低的复发风险相关(HR = 0.459)。我们根据回归分析中的显著变量构建了列线图,并使用Cox比例风险模型分析了所有亚组中对照组与SHM干预组之间的关联,以评估卒中健康管理模式的效果。本研究中的大多数患者总风险点在170至270之间。C指数值为0.76,预测复发的时间依赖性AUC>0.7。

结论

基于患者需求的卒中健康管理师指导管理模式能够更好地控制卒中危险因素,并显著降低轻至中度缺血性卒中1年内的复发率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67d3/9643216/62330ba09635/fneur-13-1018794-g0001.jpg

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