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单侧双通道内镜下腰椎管狭窄症手术的并发症:文献系统回顾和单臂研究的荟萃分析。

Complications of Unilateral Biportal Endoscopic Spinal Surgery for Lumbar Spinal Stenosis: A Systematic Review of the Literature and Meta-analysis of Single-arm Studies.

机构信息

Department of Orthopedics, Jingling Hospital, Medicine College, Nanjing University, Nanjing, China.

出版信息

Orthop Surg. 2023 Jan;15(1):3-15. doi: 10.1111/os.13437. Epub 2022 Nov 17.

Abstract

PURPOSE

This article aims to summarize the incidence of these complications through a meta-analysis, analyze the causes of complications and provide clinical promotion and recommendations.

METHODS

Databases and retrieval platform including PubMed, Web of science, Springer link, Cochrane clinical trials, ProQuest, ScienceDirect, Europe PMC, Wiley online, OVID, Clinical trials, CNKI and WanFang, and supplement the literature through Google Scholar, collect all the unilateral biportal endoscopy (UBE) controlled trials and non-controlled trials of UBE in the treatment of lumbar spinal stenosis (LSS). The search time limit is from January 1, 2000 to December 25, 2021. After two reviewers independently screened the literature, extracted data and evaluated the risk of bias in the included studies, meta-analysis was performed using Stata 15.1 software.

RESULTS

Finally, 24 studies were included, including 999 patients. The results of a single-arm rate meta-analysis showed that the overall complication rate of UBE treatment of LSS was 6.27% [95% CI (0.0412, 0.0876)], and the incidence of dural tear was 2.49% [95% CI (0.0133, 0.0390)], the incidence of transient paresthesia was 0.14% [95% CI (0.0000, 0.0072)], the incidence of postoperative spinal epidural hematoma was 0.27% [95% CI (0.0000, 0.0096)], the incidence of postop headache, inadequate decompression, root injury and infection was 0.00%.

CONCLUSION

Current evidence shows that the complication rate of UBE in the treatment of LSS is low, mainly due to dural tears. Limited by the number and quality of included studies, the above conclusions still need to be confirmed by more studies.

摘要

目的

通过荟萃分析总结这些并发症的发生率,分析并发症的原因,并提供临床推广和建议。

方法

检索PubMed、Web of science、Springer link、Cochrane 临床试验、ProQuest、ScienceDirect、Europe PMC、Wiley online、OVID、Clinical trials、CNKI 和万方等数据库和检索平台,收集所有单侧双通道内镜(UBE)治疗腰椎管狭窄症(LSS)的对照试验和非对照试验。检索时间限定为 2000 年 1 月 1 日至 2021 年 12 月 25 日。两位评审员独立筛选文献,提取数据并评估纳入研究的偏倚风险,使用 Stata 15.1 软件进行荟萃分析。

结果

最终纳入 24 项研究,共 999 例患者。单臂率荟萃分析结果显示,UBE 治疗 LSS 的总体并发症发生率为 6.27%[95%CI(0.0412,0.0876)],硬脊膜撕裂发生率为 2.49%[95%CI(0.0133,0.0390)],短暂性感觉异常发生率为 0.14%[95%CI(0.0000,0.0072)],术后脊髓硬膜外血肿发生率为 0.27%[95%CI(0.0000,0.0096)],术后头痛、减压不充分、神经根损伤和感染发生率为 0.00%。

结论

目前的证据表明,UBE 治疗 LSS 的并发症发生率较低,主要与硬脊膜撕裂有关。受纳入研究数量和质量的限制,上述结论仍需要更多研究证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b8e/9837251/1fb802aa83a0/OS-15-3-g001.jpg

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