一个大肠杆菌质粒中的IS复合转座子串联重复携带了某一基因的多个拷贝。
Multiple Copies of a Gene Are Carried by Tandem Repeats of an IS Composite Transposon in an Escherichia coli Plasmid.
作者信息
Argueta Felix, Tatarenkov Andrey, Mota-Bravo Luis
机构信息
School of Biological Sciences, University of California, Irvine, California, USA.
出版信息
Microbiol Resour Announc. 2022 Dec 15;11(12):e0066122. doi: 10.1128/mra.00661-22. Epub 2022 Nov 17.
Abstract
The fully assembled genome of Escherichia coli strain BR1220 shows a triple tandemly arrayed IS composite transposon carrying a quinolone resistance gene in a 100-kb multidrug resistance plasmid (1.6 copies per chromosome [CPC]) and a 2.6-kb Col(pHAD28) plasmid (27.8 CPC) with a nearly identical gene region.
摘要
大肠杆菌BR1220菌株的完整基因组显示，在一个100 kb的多药耐药性质粒（每染色体1.6份拷贝[CPC]）中存在一个携带喹诺酮抗性基因的三重串联排列的IS复合转座子，以及一个带有几乎相同基因区域的2.6 kb Col(pHAD28)质粒（27.8 CPC）。
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