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采用离散选择实验开发澳大利亚婴幼儿口腔健康影响量表-4 维度(ECOHIS-4D)效用值集。

Developing an Australian utility value set for the Early Childhood Oral Health Impact Scale-4D (ECOHIS-4D) using a discrete choice experiment.

机构信息

Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, School of Public Health and Social Work, Queensland University of Technology (QUT), Brisbane, Queensland, Australia.

Australian Research Centre for Population Oral Health, Adelaide Health and Medical Sciences, University of Adelaide, Adelaide, Australia.

出版信息

Eur J Health Econ. 2023 Nov;24(8):1285-1296. doi: 10.1007/s10198-022-01542-x. Epub 2022 Nov 17.

Abstract

PURPOSE

Preference-based quality of life measures (PBMs) are used to generate quality-adjusted life years (QALYs) in economic evaluations. A PBM consists of (1) a health state classification system and (2) a utility value set that allows the instrument responses to be converted to QALYs. A new, oral health-specific classification system, the Early Childhood Oral Health Impact Scale-4D (ECOHIS-4D) has recently been developed. The aim of this study was to generate an Australian utility value set for the ECOHIS-4D.

METHODS

A discrete choice experiment with duration (DCE) was used as the preference elicitation technique. An online survey was administered to a representative sample of Australian adults over 18 years. Respondents were given 14 choice tasks (10 tasks from the DCE design of 50 choice sets blocked into five blocks, 2 practice tasks, a repeated and a dominant task). Data were analyzed using the conditional logit model.

RESULTS

A total of 1201 respondents from the Australian general population completed the survey. Of them, 69% (n = 829) perceived their oral health status to be good, very good, or excellent. The estimated coefficients from the conditional logit models were in the expected directions and were statistically significant (p < 0.001). The utility values for health states defined by the ECOHIS-4D ranged from 0.0376 to 1.0000.

CONCLUSIONS

This newly developed utility value set will enable the calculation of utility values for economic evaluations of interventions related to oral diseases such as dental caries among young children. This will facilitate more effective resource allocation for oral health services.

摘要

目的

偏好加权健康相关生命质量测量(PBM)用于在经济评估中生成质量调整生命年(QALY)。PBM 由(1)健康状况分类系统和(2)效用值集组成,允许将仪器响应转换为 QALY。最近开发了一种新的、特定于口腔健康的分类系统,即儿童口腔健康影响量表-4D(ECOHIS-4D)。本研究的目的是为 ECOHIS-4D 生成澳大利亚效用值集。

方法

使用离散选择试验(DCE)作为偏好 elicitation 技术。一项针对澳大利亚 18 岁以上成年人的代表性样本的在线调查。受访者完成了 14 项选择任务(10 项来自 DCE 设计的 50 个选择集,分为 5 个块,2 个练习任务,一个重复和一个主导任务)。使用条件逻辑回归模型分析数据。

结果

共有 1201 名澳大利亚普通人群的受访者完成了调查。其中,69%(n=829)认为自己的口腔健康状况良好、很好或极佳。条件逻辑回归模型的估计系数呈预期方向且具有统计学意义(p<0.001)。ECOHIS-4D 定义的健康状况的效用值范围从 0.0376 到 1.0000。

结论

新开发的效用值集将能够计算与口腔疾病(如儿童龋齿)相关的干预措施的经济评估中的效用值。这将有助于更有效地分配口腔卫生服务资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d8/10533628/884a54e32d38/10198_2022_1542_Fig1_HTML.jpg

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