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用于牙槽嵴保存的自体颗粒状牙本质。一项系统评价。

Autogenous particulated dentin for alveolar ridge preservation. A systematic review.

作者信息

Sánchez-Labrador Luis, Bazal-Bonelli Santiago, Pérez-González Fabian, Sáez-Alcaide Luis Miguel, Cortés-Bretón Brinkmann Jorge, Martínez-González José María

机构信息

Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Spain.

Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Spain.

出版信息

Ann Anat. 2023 Feb;246:152024. doi: 10.1016/j.aanat.2022.152024. Epub 2022 Nov 14.

Abstract

PURPOSE

This review aimed to investigate the clinical outcomes of autogenous particulated dentin (APD) used for alveolar ridge preservation (ARP), evaluating volume gain, histologic/histomorphometric data, and associated complications.

MATERIAL AND METHODS

The review followed PRISMA guidelines and was registered in the International Prospective Register of Systematic Reviews (PROSPERO). An automated search was made in four databases (Medline/Pubmed, Scopus, Web of Science, and Cochrane Library) supplemented by a manual search for relevant clinical articles published before March 10th, 2022. The review included human studies of at least four patients in which extraction and subsequent ARP were performed in a single surgery. Both comparative studies and studies that assessed ARP with APD exclusively were admitted. The quality of evidence was assessed with the Cochrane bias assessment tool, the Newcastle-Ottawa Quality Assessment Scale, and the Joanna Briggs Institute Critical Appraisal tool.

RESULTS

Eleven studies fulfilled the inclusion criteria and were included for descriptive analysis, with a total of 215 patients, and 337 alveoli preserved by APD, spontaneous healing (blood clot), or other bone substitutes, obtaining comparatively less vertical and horizontal resorption when APD was used.

CONCLUSIONS

After dental extraction, autogenous dentin was effective in terms of volume maintenance, showing promising results in histologic/histomorphometric analysis, and a low complication rate. Nevertheless, few comparative studies with comparable parameters have been published and so more research providing long-term data is needed to confirm these findings.

摘要

目的

本综述旨在研究用于牙槽嵴保存(ARP)的自体颗粒牙本质(APD)的临床效果,评估体积增加、组织学/组织形态计量学数据及相关并发症。

材料与方法

本综述遵循PRISMA指南,并在国际系统评价前瞻性注册库(PROSPERO)中进行了注册。在四个数据库(Medline/Pubmed、Scopus、Web of Science和Cochrane图书馆)中进行了自动检索,并辅以手动检索2022年3月10日前发表的相关临床文章。该综述纳入了至少四名患者的人体研究,其中拔牙及随后的ARP在同一手术中进行。比较研究和仅评估APD进行ARP的研究均被纳入。使用Cochrane偏倚评估工具、纽卡斯尔-渥太华质量评估量表和乔安娜·布里格斯研究所批判性评价工具对证据质量进行评估。

结果

11项研究符合纳入标准,纳入进行描述性分析,共有215例患者,337个牙槽通过APD、自发愈合(血凝块)或其他骨替代物得以保存,使用APD时垂直和水平吸收相对较少。

结论

拔牙后,自体牙本质在维持体积方面有效,在组织学/组织形态计量学分析中显示出有前景的结果,且并发症发生率低。然而,很少有具有可比参数的比较研究发表,因此需要更多提供长期数据的研究来证实这些发现。

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