Minetti Elio, Taschieri Silvio, Corbella Stefano
Department of Biomedical, Surgical, and Dental Science, Università degli Studi di Milano, Viale Pisa 10, 20146 Milan, Italy.
IRCCS Istituto Ortopedico Galeazzi, 20157 Milan, Italy.
Materials (Basel). 2025 May 27;18(11):2518. doi: 10.3390/ma18112518.
: To reconstruct and maintain hard tissues over time, it is necessary to follow effective protocols and use appropriate materials. The selection of the graft material and its properties can also affect the final outcomes. For this purpose, numerous graft materials have been suggested. Among the valuable alternatives to these biomaterials, interest in using teeth as graft material has grown in recent years. : The aim of the study was to investigate the histomorphometric outcomes of using tooth-derived materials when used as a bone substitute. : We evaluated the histological results of autologous demineralized tooth graft material prepared using a Tooth Transformer device. A total of 187 histological samples from 186 subjects (52% male and 48% female, with an average age of 56.30 ± 12.97 years) were analyzed. The analysis focused on the total bone volume (BV%), residual tooth material (residual graft, TT%), and vital bone (VB%). The differences between the presence and absence of the resorbable membrane were also analyzed. : The amount of VB was 36.28 ± 19.09%, the residual graft TT was 9.6 ± 10.76%, and 46.96 ± 13.85% was the total bone volume (BV). The presence of membrane increased the amount of BV% and reduced the time to produce bone. : The procedure using demineralized autologous tooth-derived biomaterial may be a predictable method for producing new vital bone capable of supporting dental implant rehabilitation and the use of membrane allow better results.
为了长期重建和维持硬组织,有必要遵循有效的方案并使用合适的材料。移植材料的选择及其特性也会影响最终结果。为此,人们提出了许多移植材料。在这些生物材料的有价值的替代物中,近年来将牙齿用作移植材料的兴趣有所增加。
本研究的目的是调查使用牙齿衍生材料作为骨替代物时的组织形态计量学结果。
我们评估了使用牙齿转化器装置制备的自体脱矿牙齿移植材料的组织学结果。对来自186名受试者(52%为男性,48%为女性,平均年龄56.30±12.97岁)的187个组织学样本进行了分析。分析重点关注总骨体积(BV%)、残留牙齿材料(残留移植物,TT%)和活性骨(VB%)。还分析了可吸收膜存在与否之间的差异。
VB的量为36.28±19.09%,残留移植物TT为9.6±10.76%,总骨体积(BV)为46.96±13.85%。膜的存在增加了BV%的量并缩短了骨生成时间。
使用脱矿自体牙齿衍生生物材料的程序可能是一种可预测的方法,用于生成能够支持牙种植体修复的新的活性骨,并且使用膜可获得更好的结果。