Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), Stockholm, Sweden.
Institute of Clinical Sciences, Department of Obstetrics and Gynaecology, Unit of Reproduction Epidemiology, Tornblad Institute, Lund University, Lund, Sweden.
Value Health. 2023 May;26(5):639-648. doi: 10.1016/j.jval.2022.10.003. Epub 2022 Nov 14.
There is a lack of consensus around the definition of delivery by cesarean section (CS) on maternal request, and clinical practice varies across and within countries. Previous economic evaluations have focused on specific populations and selected complications. Our aim was to evaluate the cost-effectiveness of CS on maternal request compared with planned vaginal birth in a Swedish context, based on a systematic review of benefits and drawbacks and national registry data on costs.
We used the results from a systematic literature review of somatic risks for long- and short-term complications for mother and child, in which certainty was rated low, moderate, or high using the Grading of Recommendations Assessment, Development and Evaluation. Swedish national registry data were used for healthcare costs of delivery and complications. Utilities for long-term complications were based on a focused literature review. We constructed a decision tree and conducted separate analyses for primi- and multiparous women. Costs and effects were discounted by 3% and the time horizon was varied between 1 and 20 years.
Planned vaginal birth leads to lower healthcare costs and somatic health gains compared with elective CS without medical indication over up to 20 years. Although there is uncertainty around, for example, quality-of-life effects, results remain stable across sensitivity analyses.
CS on maternal request leads to increased hospitalization costs in a Swedish setting, taking into account short- and long-term consequences for both mother and child. Future research needs to study the psychological consequences related to different delivery methods, costs in outpatient care, and productivity losses.
由于对基于产妇要求的剖宫产(CS)定义缺乏共识,且临床实践在国家之间和国家内部存在差异,因此之前的经济评估都集中在特定人群和选定的并发症上。我们的目的是根据对利益和弊端的系统评价以及关于成本的国家登记数据,在瑞典背景下评估基于产妇要求的 CS 与计划阴道分娩相比的成本效益。
我们使用了对母亲和儿童的长期和短期并发症的躯体风险的系统文献综述的结果,其中使用推荐评估、制定和评估的分级方法对确定性进行了低、中或高的评级。瑞典国家登记数据用于分娩和并发症的医疗保健成本。长期并发症的效用基于重点文献综述。我们构建了决策树,并为初产妇和经产妇分别进行了分析。成本和效果以 3%的贴现率贴现,时间范围在 1 至 20 年之间变化。
在长达 20 年的时间内,与无医学指征的选择性 CS 相比,计划阴道分娩可降低医疗保健成本并改善躯体健康,尽管在生活质量影响等方面存在不确定性,但结果在敏感性分析中仍然稳定。
在考虑到母婴短期和长期后果的情况下,在瑞典,基于产妇要求的 CS 会导致住院费用增加。未来的研究需要研究与不同分娩方式相关的心理后果、门诊护理成本和生产力损失。