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口香糖在剖宫产术后肠梗阻中的疗效:一项随机临床试验

[Efficacy of chewing gum in post-cesarean ileus: A randomized clinical trial].

作者信息

Cortes-Cernas Vania Itzel, Salas-Gutiérrez María de Lourdes, Vargas-Ledesma Reyna Mariela, Cruz-Plascencia Marina, Reveles-Alba Kevin Alejandro, Reyes-Sosa Arturo Maximiliano, González Alma Patricia, Paque-Bautista Carlos, Luna-Anguiano José Luis Felipe, Sosa-Bustamante Gloria Patricia

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No. 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No. 48, Servicio de Obstetricia. León, Guanajuato, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2025 Jan 3;63(1):e6501. doi: 10.5281/zenodo.14200085.

DOI:10.5281/zenodo.14200085
PMID:40267281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12077920/
Abstract

BACKGROUND

The use of chewing gum postoperatively has been shown to be useful in the recovery of postoperative ileus.

OBJECTIVE

To evaluate the efficacy of using chewing gum as simulated feeding for the recovery of postoperative ileus after cesarean section.

MATERIAL AND METHODS

Randomized, controlled, double-blind clinical trial in women ≥ 18 years, during the postoperative period of cesarean section, distributed in 2 groups, group A (chewing gum, n = 63) and group B (control, n = 63). The postoperative time elapsed until the first flatus, the presence of evacuation during the postoperative period before hospital discharge, and the time elapsed until the first postoperative evacuation and length of hospital stay (HS) were evaluated.

RESULTS

126 patients were included. Postoperative evacuation before hospital discharge was more frequent in group A (p = 0.01); in addition, there was a shorter length of HS (p = 0.04); no patient presented nausea during the postoperative period (p = 0.0001). No difference was observed between the study groups regarding the time to onset of first flatus (p = 0.17), or the time elapsed to first postoperative evacuation (p = 0.07). The number needed to treat (NNT) was 5 and the absolute risk reduction (ARR) was 21%, for both the presence of nausea and the absence of postoperative evacuation. No patient reported complications.

CONCLUSIONS

The use of chewing gum as simulated feeding after cesarean section is effective and safe for recovery from postoperative ileus.

摘要

背景

术后咀嚼口香糖已被证明对术后肠梗阻的恢复有益。

目的

评估咀嚼口香糖作为模拟进食对剖宫产术后肠梗阻恢复的疗效。

材料与方法

对年龄≥18岁的剖宫产术后女性进行随机、对照、双盲临床试验,分为两组,A组(咀嚼口香糖,n = 63)和B组(对照组,n = 63)。评估直至首次排气的术后时间、出院前术后期间的排便情况、直至首次术后排便的时间以及住院时间(HS)。

结果

纳入126例患者。A组出院前术后排便更频繁(p = 0.01);此外,住院时间更短(p = 0.04);术后期间无患者出现恶心(p = 0.0001)。在首次排气时间(p = 0.17)或首次术后排便时间(p = 0.07)方面,研究组之间未观察到差异。对于恶心的发生和术后未排便情况,治疗所需人数(NNT)为5,绝对风险降低(ARR)为21%。无患者报告并发症。

结论

剖宫产术后使用咀嚼口香糖作为模拟进食对术后肠梗阻的恢复有效且安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/aed66848ee5e/04435117-63-1-e6501-c004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/ab89baf507a4/04435117-63-1-e6501-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/08b13672d025/04435117-63-1-e6501-c001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/ba45c3fa644e/04435117-63-1-e6501-c002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/2556d24c3560/04435117-63-1-e6501-c003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/aed66848ee5e/04435117-63-1-e6501-c004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/ab89baf507a4/04435117-63-1-e6501-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/08b13672d025/04435117-63-1-e6501-c001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/ba45c3fa644e/04435117-63-1-e6501-c002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/2556d24c3560/04435117-63-1-e6501-c003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b030/12077920/aed66848ee5e/04435117-63-1-e6501-c004.jpg

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本文引用的文献

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Cureus. 2024 Aug 30;16(8):e68210. doi: 10.7759/cureus.68210. eCollection 2024 Aug.
2
Effects of Postoperative Gum Chewing on Recovery of Gastrointestinal Function Following Laparoscopic Gynecologic Surgery: Systematic Review and Meta-Analysis of Randomized Controlled Trials.术后咀嚼口香糖对腹腔镜妇科手术后胃肠功能恢复的影响:随机对照试验的系统评价和荟萃分析
J Clin Med. 2024 May 12;13(10):2851. doi: 10.3390/jcm13102851.
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Effect of chewing gum on anxiety in women undergoing elective cesarean section: a randomized controlled study.
咀嚼口香糖对行择期剖宫产术的妇女焦虑的影响:一项随机对照研究。
Ann Palliat Med. 2023 May;12(3):529-537. doi: 10.21037/apm-22-811. Epub 2023 Mar 16.
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Effect of Chewing Gum on Duration of Postoperative Ileus Following Laparotomy for Gastroduodenal Perforations: Protocol for a Randomized Controlled Trial.口香糖对胃十二指肠穿孔剖腹术后肠梗阻持续时间的影响:一项随机对照试验方案
Int J Surg Protoc. 2023 Feb 6;27(1):9-17. doi: 10.29337/ijsp.188. eCollection 2023.
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Economic Evaluation of Elective Cesarean Section on Maternal Request Compared With Planned Vaginal Birth-Application to Swedish Setting Using National Registry Data.经济评价:产妇要求选择性剖宫产与计划阴道分娩的比较——基于全国登记数据的瑞典应用。
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Prevention and Management of Postoperative Ileus: A Review of Current Practice.术后肠梗阻的预防与管理:当前实践综述
Cureus. 2022 Feb 27;14(2):e22652. doi: 10.7759/cureus.22652. eCollection 2022 Feb.
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