Department of Physical Education, Sejong University, Seoul, South Korea.
Department of Physical Education, Yonsei University, Seoul, South Korea.
Medicine (Baltimore). 2022 Nov 11;101(45):e31246. doi: 10.1097/MD.0000000000031246.
Metabolic disorder is globally prevalent in children and adolescents, and physical activity may have a protective role against metabolic disorder. However, the association between metabolic equivalent (MET) and visceral adiposity index (VAI) among children and adolescents remains unclear. This study aimed to address this concern. Data were retrieved from the National Health and Nutrition Examination Survey (NHANES), which used the Global Physical Activity Questionnaire to assess the physical activity levels. VAI was calculated according to body mass index (BMI), waist circumference (WC), triglyceride (TG), and high-density lipoprotein (HDL). Linear regression was adopted to assess the association between MET and VAI. Restricted cubic spline regression was used to further explore the nonlinear relationship, Interaction effect analysis was conducted to identify whether the sample characteristic could modify the effect of MET on VAI. After data cleansing, a total of 3402 participants aged <18 years were enrolled. In the fully adjusted linear regression model, the β for VAI was 0.01 (95% confidence interval [CI]: -0.08, 0.09) for the second tertile and -0.11 (95% CI: -0.20, -0.03) for the third tertile. A linear downward trend was found in the restricted cubic spline regression (overall P < .05). Interaction effect analysis revealed no significant effects of age, gender, race, income poverty ratio, and insurance (all P for interaction >0.05). High physical activity intensity is associated with decreased VAI scores in children and adolescents.
代谢紊乱在儿童和青少年中普遍存在，而身体活动可能对代谢紊乱具有保护作用。然而，儿童和青少年的代谢当量（MET）与内脏脂肪指数（VAI）之间的关联尚不清楚。本研究旨在解决这一问题。数据来自国家健康和营养检查调查（NHANES），该调查使用全球体力活动问卷来评估身体活动水平。VAI 根据体重指数（BMI）、腰围（WC）、甘油三酯（TG）和高密度脂蛋白（HDL）计算。采用线性回归来评估 MET 与 VAI 之间的关联。采用受限立方样条回归进一步探讨非线性关系，进行交互作用分析以确定样本特征是否可以改变 MET 对 VAI 的影响。在数据清理后，共纳入了 3402 名年龄<18 岁的参与者。在完全调整的线性回归模型中，第二三分位的 VAI 的 β 值为 0.01（95%置信区间 [CI]：-0.08，0.09），第三三分位的 β 值为-0.11（95% CI：-0.20，-0.03）。受限立方样条回归显示出线性下降趋势（整体 P<0.05）。交互作用分析显示，年龄、性别、种族、收入贫困率和保险（所有交互作用 P 值均>0.05）对效应没有显著影响。高强度的身体活动与儿童和青少年的 VAI 评分降低有关。
