Rai Dolly, Shukla Deepankar, Bhola Nitin D
Oral and Maxillofacial Surgery, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2022 Oct 11;14(10):e30191. doi: 10.7759/cureus.30191. eCollection 2022 Oct.
Aspergillosis is a disease that can manifest itself in both invasive and non-invasive forms. Noninvasive aspergillosis usually affects a healthy host, manifesting as a fungal hyphae cluster or an allergy. In a healthy host, localized invasive infection of damaged tissue is prevalent, but in immunocompromised patients, more extensive infection is often evident, which carries a high mortality rate. Invasive aspergillosis of the paranasal sinuses is a rare condition that is frequently misdiagnosed. Histological analysis and fungal culture are used to make a definitive diagnosis. The purpose of this study is to discuss a case of COVID-19-induced aspergillosis involving the maxillary sinus in an immunocompromised patient, with a focus on early diagnosis because fungi have a predisposition to invade nearby blood vessels and embolize to distant organs, making a delay in treatment which is life-threatening.
曲霉病是一种可表现为侵袭性和非侵袭性形式的疾病。非侵袭性曲霉病通常影响健康宿主，表现为真菌菌丝团或过敏反应。在健康宿主中，受损组织的局部侵袭性感染较为常见，但在免疫功能低下的患者中，往往会出现更广泛的感染，且死亡率很高。鼻窦侵袭性曲霉病是一种罕见疾病，常被误诊。组织学分析和真菌培养用于明确诊断。本研究的目的是讨论一例免疫功能低下患者由 COVID-19 诱发的累及上颌窦的曲霉病病例，重点关注早期诊断，因为真菌易于侵入附近血管并栓塞至远处器官，会导致治疗延误，危及生命。
