MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, National Institute for Health Research Nottingham Biomedical Research Centre, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital, Uttoxeter Road, Derby, DE22 3DT, UK.
Applied Medical Sciences, Clinical Nutrition Department, Jazan University, Jazan, Kingdom of Saudi Arabia.
Obes Surg. 2023 Jan;33(1):313-331. doi: 10.1007/s11695-022-06197-4. Epub 2022 Nov 19.
In this review, we collated evidence relating to taste change and zinc deficiency in relation to bariatric surgery (BS) and effects of zinc replacement on taste perception and speculate on the possible role of zinc deficiency to induce taste change after BS. A literature search was conducted (33 studies, N = 3264). We showed that taste change and zinc deficiency are frequent complications after BS, which both typically occurred at 6 months post-surgery. Our analysis did not support a causal link between the two, but similar onset of incidences indirectly indicates a link. Supplementation with 45-50 mg of zinc sulphate, higher than current recommendation, was effective in improving taste. Further studies are required to establish the causal link between the two in the context of BS.
在这篇综述中，我们整理了与减重手术（BS）相关的味觉改变和锌缺乏的证据，以及锌替代对味觉感知的影响，并推测锌缺乏在 BS 后味觉改变中的可能作用。我们进行了文献检索（33 项研究，N=3264）。结果表明，味觉改变和锌缺乏是 BS 后的常见并发症，通常发生在手术后 6 个月。我们的分析不支持两者之间存在因果关系，但发病时间相似间接表明两者之间存在关联。补充 45-50 毫克硫酸锌，高于目前的建议量，可有效改善味觉。需要进一步的研究来确定两者在 BS 背景下的因果关系。
