Department of Surgery, University Hospital of Larissa, University of Thessaly, Viopolis, 41110, Larissa, Greece.
Department of Surgery, Iaso Thessalias, Larissa, Greece.
Obes Surg. 2018 Dec;28(12):3929-3934. doi: 10.1007/s11695-018-3433-3.
The aim of this study was to evaluate the prevalence of hair loss after laparoscopic sleeve gastrectomy (LSG). The effects of variables on the likelihood that patients developed hair loss were also examined.
Fifty patients who underwent LSG were enrolled in this prospective study. Demographics, hematocrit, iron, zinc, folic acid, vitamin B12, total proteins, and albumin were evaluated preoperatively and 6 months postoperatively.
Hair loss was observed in 56% of patients and particularly in 46% in females and in 10% in males. Analysis of variance indicated statistical differences for hair loss among the groups with and without hair loss concerning preoperative zinc (p < 0.001), postoperative zinc (p < 0.001), preoperative B12 (p < 0.001), postoperative B12 (p < 0.001), postoperative folic acid (p = 0.039), and postoperative use of supplements (p < 0.001). Patients with hair loss had lower values of zinc preoperatively and postoperatively compared to patients without hair loss (0.61 vs 0.81 mcg/ml) (0.46 vs 0.73 mcg/ml) and also lower values of vitamin B12 preoperatively and postoperatively compared to patients without hair loss (243.04 vs 337.41 pg/ml) (261.54 vs 325.68 pg/ml). Interestingly, the zinc levels were normal preoperatively and lower to normal levels postoperatively and the levels of vitamin B12 were lower than normal values preoperatively in patients with hair loss. Patients with hair loss had mean lower levels of postoperative folic acid of 8 ng/ml.
The prevalence of hair loss was 56% 6 months after LSG. Preoperative monitoring and counseling of these micronutrients may be a preventive and therapeutic measure.
本研究旨在评估腹腔镜袖状胃切除术（LSG）后脱发的发生率。还检查了变量对患者脱发可能性的影响。
这项前瞻性研究纳入了 50 名接受 LSG 的患者。评估了术前和术后 6 个月的人口统计学数据、血细胞比容、铁、锌、叶酸、维生素 B12、总蛋白和白蛋白。
56%的患者出现脱发，女性中脱发的比例尤其高（46%），男性中脱发的比例低（10%）。方差分析表明，术前和术后锌（p<0.001）、术前 B12（p<0.001）、术后 B12（p<0.001）、术后叶酸（p=0.039）和术后补充剂的使用（p<0.001）在有脱发和无脱发的组之间存在统计学差异。脱发患者的锌值术前和术后均低于无脱发患者（0.61 与 0.81μg/ml）（0.46 与 0.73μg/ml），且维生素 B12 值术前和术后均低于无脱发患者（243.04 与 337.41pg/ml）（261.54 与 325.68pg/ml）。有趣的是，脱发患者的锌水平在术前正常，术后低于正常水平，而脱发患者的维生素 B12 水平在术前低于正常值。脱发患者的术后叶酸平均水平为 8ng/ml。
LSG 术后 6 个月脱发的发生率为 56%。这些微量营养素的术前监测和咨询可能是一种预防和治疗措施。
