瑜伽对哮喘患者肺功能的影响:一项荟萃分析。

The effect of yoga on pulmonary function in patients with asthma: A meta-analysis.

作者信息

Singh Narendra, Deka Sangeeta, Saraswati Priyanka, Sindhwani Girish, Goel Arun, Kumari Ranjeeta

机构信息

Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh, India.

Department of Yogic Science, University of Patanjali, Haridwar, India.

出版信息

Complement Ther Clin Pract. 2023 Feb;50:101682. doi: 10.1016/j.ctcp.2022.101682. Epub 2022 Nov 8.

Abstract

BACKGROUND

Asthma is one of the most common non-communicable diseases. Yoga with physical postures, breathing exercises, meditation, and relaxation may play an essential role in the complementary management of lower respiratory diseases. The study aimed to evaluate the impact of yoga (posture, breathing exercises, and meditation) on pulmonary function tests, asthma control tests, and health-related quality of adult asthmatic patients.

METHODS

MEDLINE, PubMed, Embase, Cochrane, Scopus, Google Scholar, ResearchGate, Clinical Key, and Academia electronic search engines were explored to search the relevant literature. The present study included adult asthmatic patients (age -18 and 60 years) with mild to moderate asthma, per GINA (Global Initiative for Asthma) guidelines. The effect of yoga was assessed on the following outcomes; pulmonary function tests, including FeV1 (Forced expiratory volume 1 s), FVC (Forced vital capacity), FeV1/FVC, peak expiratory flow rate (PEFR), health-related quality of life, and asthma control test. A fixed-effect model was applied to compute significance for statistical heterogeneity. P-value <0.05 was considered for statistical significance.

RESULTS

Finally, fifteen articles were included for meta-analysis. The forest plot for overall effect of yoga intervention and usual care favors the yoga intervention for improvement in pulmonary function as FeV1 (SMD = 0.96, CI = 0.77-1.14, I = 54%), FVC (SMD = 0.35, CI = 0.14-0.55, p = 0.11, I = 50%), Fev1/FVC (SMD = 0.18, CI = -0.38-0.02, p = 0.02, I = 50%), PEFR (SMD = 0.38, CI = 0.18-0.58, p = 0.0003, I = 0%), asthma control test (SMD = 0.16, CI = 0.15-0.48, p = 0.31, I = 86%) and health-related quality of life (SMD = 0.26, CI = 0.18-0.34, p = 0.02, I = 51%) of asthmatic patients.

CONCLUSION

This meta-analysis provides a moderate level of evidence regarding yoga as a complementary therapy in managing mild to moderate asthmatic patients. It also adds to the current knowledge of the same.

摘要

背景

哮喘是最常见的非传染性疾病之一。包含体式、呼吸练习、冥想和放松的瑜伽可能在辅助治疗下呼吸道疾病中发挥重要作用。本研究旨在评估瑜伽(体式、呼吸练习和冥想)对成年哮喘患者肺功能测试、哮喘控制测试及健康相关生活质量的影响。

方法

检索MEDLINE、PubMed、Embase、Cochrane、Scopus、谷歌学术、ResearchGate、Clinical Key和Academia等电子搜索引擎以查找相关文献。根据全球哮喘防治创议(GINA)指南,本研究纳入年龄在18至60岁之间的轻度至中度哮喘成年患者。评估瑜伽对以下结果的影响:肺功能测试,包括第1秒用力呼气量(FeV1)、用力肺活量(FVC)、FeV1/FVC、呼气峰值流速(PEFR)、健康相关生活质量及哮喘控制测试。应用固定效应模型计算统计异质性的显著性。P值<0.05被视为具有统计学意义。

结果

最终,纳入15篇文章进行荟萃分析。瑜伽干预和常规护理总体效果的森林图显示,瑜伽干预有利于改善哮喘患者的肺功能,如FeV1(标准化均数差[SMD]=0.96,可信区间[CI]=0.77-1.14,I²=54%)、FVC(SMD=0.35,CI=0.14-0.55,p=0.11,I²=50%)、Fev1/FVC(SMD=0.18,CI=-0.38-0.02,p=0.02,I²=50%)、PEFR(SMD=0.38,CI=0.18-0.58,p=0.0003,I²=0%)、哮喘控制测试(SMD=0.16,CI=0.15-0.48,p=0.31,I²=86%)以及健康相关生活质量(SMD=0.26,CI=0.18-0.34,p=0.02,I²=51%)。

结论

这项荟萃分析提供了一定程度的证据,表明瑜伽可作为辅助疗法用于管理轻度至中度哮喘患者。它也增加了关于这方面的现有知识。

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