冠状动脉造影术前阻塞性睡眠呼吸暂停筛查。

Screening for obstructive sleep apnea before coronary angiography.

机构信息

Department of Sleep Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, China.

School of Medicine, South China University of Technology, Guangzhou, China.

出版信息

Clin Respir J. 2023 Jan;17(1):13-19. doi: 10.1111/crj.13556. Epub 2022 Nov 20.

DOI:10.1111/crj.13556

PMID:36404580

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9829612/

Abstract

INTRODUCTION

The prevalence of obstructive sleep apnea (OSA) in patients with suspected coronary heart disease (CHD) is yet to be clarified. This study aimed to investigate the prevalence of OSA before coronary angiography (CAG).

METHODS

We retrospectively evaluated patients with suspected CHD admitted to the Department of Geriatric Cardiology of our hospital between July 2019 and July 2021. OSA was screened using the level III home sleep apnea test before CAG. The prevalence of OSA was then compared between the CHD and non-CHD groups. CHD severity was determined using the Gensini score of CAG results, and OSA severity was graded using the apnea-hypopnea index (AHI).

RESULTS

Among the 327 patients, 211 had CHD. In total, 264 patients were diagnosed with OSA (80.7%) (184 patients, CHD group [87.2%]; 80 patients, non-CHD group [69.0%]). The CHD group had a significantly higher prevalence of OSA (P < 0.01) and higher AHI (CHD group 18.76 ± 14.94, non-CHD group 11.56 ± 10.67, P < 0.01). The Gensini score was positively correlated with OSA severity in patients with CHD, and AHI ≥ 20 was a risk factor for CHD (odds ratio: 1.961, 95% confidence interval: 1.065-3.608, P < 0.05).

CONCLUSION

OSA screening before CAG revealed a higher prevalence in CHD patients than in non-CHD patients. The degree of coronary artery obstruction is positively correlated with AHI, and AHI ≥ 20 is a risk factor for CHD. Therefore, attention should be paid to OSA screening and management before CAG in patients with suspected CHD.

摘要

简介

阻塞性睡眠呼吸暂停（OSA）在疑似冠心病（CHD）患者中的流行情况尚不清楚。本研究旨在调查冠状动脉造影（CAG）前 OSA 的患病率。

方法

我们回顾性评估了 2019 年 7 月至 2021 年 7 月期间我院老年心脏病科收治的疑似 CHD 患者。在 CAG 前使用三级家庭睡眠呼吸暂停试验筛查 OSA。然后比较 CHD 组和非 CHD 组之间 OSA 的患病率。CHD 严重程度根据 CAG 结果的 Gensini 评分确定，OSA 严重程度采用呼吸暂停低通气指数（AHI）分级。

结果

在 327 名患者中，211 名患有 CHD。共有 264 名患者被诊断为 OSA（80.7%）（184 名患者，CHD 组[87.2%]；80 名患者，非 CHD 组[69.0%]）。CHD 组 OSA 患病率显著较高（P < 0.01），AHI 较高（CHD 组 18.76 ± 14.94，非 CHD 组 11.56 ± 10.67，P < 0.01）。CHD 患者的 Gensini 评分与 OSA 严重程度呈正相关，AHI≥20 是 CHD 的危险因素（优势比：1.961，95%置信区间：1.065-3.608，P < 0.05）。