妇科癌症手术女性下肢淋巴水肿相关生活质量的决定因素。
Determinants of quality of life related to lower limb lymphedema in women with gynecological cancer surgery.
作者信息
Hsu Yu-Yun, Liu Chia-Yu, Ho Chien-Liang, Hsu Keng-Fu
机构信息
Department of Nursing, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Nursing Department, National Cheng Kung University Hospital, Tainan, Taiwan.
出版信息
Asia Pac J Oncol Nurs. 2022 Oct 3;10(1):100153. doi: 10.1016/j.apjon.2022.100153. eCollection 2023 Jan.
OBJECTIVE
This study aimed to identify the predictors of quality of life (QoL) related to lower limb lymphedema among women who had undergone gynecological cancer surgery. Additionally, the association between fatigue and the QoL was examined.
METHODS
A cross-sectional design with a convenience sample was adopted. Participants included 200 women with lymphadenectomy following gynecological cancer surgery. Demographic data, QoL related to lower limb lymphedema, and fatigue symptoms were collected.
RESULTS
Of the 200 participants, 60 percent ( = 120) reported a mild to severe impact on QoL related to lower limb lymphedema, with the main impact on the function of mobility and physical symptoms. Age less than 55 years (β = 0.706, OR = 2.027, = 0.017), a diagnosis of ovarian cancer (β = 0.804, OR = 2.235, = 0.048), undergoing chemotherapy (β = 0.616, OR = 1.854, = 0.046), time after surgery (β = -0.833, OR = 0.435, = 0.05), and fatigue (β = 0.055, OR = 1.06, < 0.001) were independently associated with QoL related to lower limb lymphedema. Hierarchical multiple regression demonstrated that fatigue was significantly associated with QoL related to lower limb lymphedema after controlling for age, types of cancer, time after surgery, and chemotherapy. Fatigue explained 11% of the variance in the QoL.
CONCLUSIONS
More than half of the women with gynecological cancer requiring lymphadenectomy experienced an impact on QoL related to lower limb lymphedema. Effective interventions are warranted to improve the QoL related to lower limb lymphedema among women with gynecological cancer, particularly those who present with fatigue.
目的
本研究旨在确定接受妇科癌症手术的女性中与下肢淋巴水肿相关的生活质量（QoL）预测因素。此外，还研究了疲劳与生活质量之间的关联。
方法
采用便利抽样的横断面设计。参与者包括200名接受妇科癌症手术后进行淋巴结清扫术的女性。收集了人口统计学数据、与下肢淋巴水肿相关的生活质量以及疲劳症状。
结果
在200名参与者中，60%（n = 120）报告下肢淋巴水肿对生活质量有轻度至重度影响，主要影响活动功能和身体症状。年龄小于55岁（β = 0.706，OR = 2.027，P = 0.017）、卵巢癌诊断（β = 0.804，OR = 2.235，P = 0.048）、接受化疗（β = 0.616，OR = 1.854，P = 0.046）、术后时间（β = -0.833，OR = 0.435，P = 0.05）和疲劳（β = 0.055，OR = 1.06，P < 0.001）与下肢淋巴水肿相关的生活质量独立相关。分层多元回归表明，在控制年龄、癌症类型、术后时间和化疗后，疲劳与下肢淋巴水肿相关的生活质量显著相关。疲劳解释了生活质量变异的11%。
结论
超过一半需要进行淋巴结清扫术的妇科癌症女性经历了下肢淋巴水肿对生活质量的影响。有必要采取有效干预措施来改善妇科癌症女性与下肢淋巴水肿相关的生活质量，特别是那些有疲劳症状的女性。
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