Naz Arooj, Hassan Muhammad, Ho Kimberley
Medicine, Frontier Medical and Dental College, Abbottabad, PAK.
Internal Medicine, Akhtar Saeed Medical and Dental College, Lahore, PAK.
Cureus. 2022 Oct 17;14(10):e30394. doi: 10.7759/cureus.30394. eCollection 2022 Oct.
Hypereosinophilic syndrome, a rare condition, is characterized by eosinophilia with associated organ infiltration and organ failure. The most commonly involved sites include the cardiovascular, gastrointestinal, and central nervous systems. Infiltration of eosinophils into the myocytes may result in congestive heart failure warranting the use of a left ventricular assist device (LVAD). The authors describe a case of a 76-year-old male with dyspnea and a consistently elevated eosinophil count. Initially diagnosed with adult-onset asthma, he failed to improve despite his adherence to recommended pharmacological treatment. The exacerbation of dyspnea combined with the signs of congestive heart failure led to the evaluation of LVAD therapy in this patient.
嗜酸性粒细胞增多综合征是一种罕见疾病,其特征为嗜酸性粒细胞增多并伴有相关器官浸润和器官功能衰竭。最常受累的部位包括心血管系统、胃肠道和中枢神经系统。嗜酸性粒细胞浸润心肌细胞可能导致充血性心力衰竭,需要使用左心室辅助装置(LVAD)。作者描述了一例76岁男性患者,该患者有呼吸困难且嗜酸性粒细胞计数持续升高。最初被诊断为成人发作性哮喘,尽管他坚持推荐的药物治疗,但病情并未改善。呼吸困难加重并伴有充血性心力衰竭的体征,促使对该患者进行LVAD治疗评估。