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创伤性髋部骨折的手术时间会影响髂筋膜阻滞的疗效吗?一篇简短报告。

Does time to surgery for traumatic hip fracture impact the efficacy of fascia iliaca blocks? A brief report.

作者信息

Akinola Kerrick, Salottolo Kristin, Meinig Richard, Fine Landon, Madayag Robert M, Ekengren Francie, Tanner Allen, Bar-Or David

机构信息

Trauma Services Department, St Anthony Hospital, Lakewood, Colorado, USA.

Trauma Research, St Anthony Hospital & Medical Campus, Lakewood, Colorado, USA.

出版信息

Trauma Surg Acute Care Open. 2022 Nov 15;7(1):e000970. doi: 10.1136/tsaco-2022-000970. eCollection 2022.

Abstract

OBJECTIVES

Outcomes after traumatic hip fracture have shown to be significantly improved with timely surgical management. This study determined whether there were differences in efficacy of fascia iliaca compartment block (FICB) on pain outcomes in patients with hip fracture, once stratified by time to surgery.

METHODS

Trauma patients (55-90 years) admitted to five Level I/II trauma centers within 12 hours of hip fracture were included. Patients with coagulopathy, significant multi-trauma (injury severity score >16), bilateral hip fractures, and postoperative FICBs were excluded. The primary exposure was analgesia modality: adjunctive FICB or systemic analgesics (no FICB). Study endpoints were incidence of delirium through 48 hours postoperatively (%), preoperative and postoperative oral morphine equivalents (OMEs), and preoperative and postoperative pain (0-10 scale). Adjusted regression models were used to examine the effect of FICB on outcomes; all models were stratified by time from arrival to surgery, ≤24 hours (earlier surgery; n=413) and >24 hours (later surgery; n=143).

RESULTS

FICB use was similar with earlier and later surgery (70.2% vs 76.2%), and there were no demographic differences by utilization of FICB, by time to surgery. In the earlier surgery group, preoperative pain was lower for patients with FICB versus no FICB (3.6 vs 4.5, p<0.001), with no difference by FICB for delirium (OR 1.00, p>0.99) or OMEs (p=0.75 preoperative, p=0.91 postoperative). In the later surgery group, there was a nearly twofold reduction in preoperative OMEs with FICB than no FICB (25.5 mg vs 45.2 mg, p=0.04), with no differences for delirium (OR 4.21, p=0.18), pain scores (p=0.25 preoperative, p=0.27 postoperative), and postoperative OMEs (p=0.34).

CONCLUSIONS

Compared with systemic analgesia, FICB resulted in improved pain scores at the preoperative assessment among patients with earlier surgery, whereas FICB reduced opioid consumption over the preoperative period only when surgery was later than 24 hours from arrival.

LEVEL OF EVIDENCE

II, prospective, therapeutic.

摘要

目的

创伤性髋部骨折后,及时的手术治疗已显示能显著改善预后。本研究确定了按手术时间分层后,髂筋膜间隙阻滞(FICB)对髋部骨折患者疼痛预后的疗效是否存在差异。

方法

纳入在髋部骨折后12小时内入住5家一级/二级创伤中心的创伤患者(55 - 90岁)。排除有凝血功能障碍、严重多发伤(损伤严重度评分>16)、双侧髋部骨折以及术后接受FICB治疗的患者。主要暴露因素为镇痛方式:辅助性FICB或全身镇痛药(无FICB)。研究终点为术后48小时内谵妄的发生率(%)、术前和术后口服吗啡当量(OME)以及术前和术后疼痛(0 - 10分)。采用校正回归模型检验FICB对预后的影响;所有模型按从入院到手术的时间分层,≤24小时(早期手术;n = 413)和>24小时(晚期手术;n = 143)。

结果

早期手术和晚期手术中FICB的使用情况相似(70.2%对76.2%),按手术时间和FICB的使用情况来看,在人口统计学方面没有差异。在早期手术组中,接受FICB治疗的患者术前疼痛低于未接受FICB治疗的患者(3.6对4.5,p<0.001),FICB对谵妄(比值比1.00,p>0.99)或OME(术前p = 0.75,术后p = 0.91)没有影响。在晚期手术组中,接受FICB治疗的患者术前OME比未接受FICB治疗的患者减少了近两倍(25.5毫克对45.2毫克,p = 0.04),在谵妄(比值比4.21,p = 0.18)、疼痛评分(术前p = 0.25,术后p = 0.27)和术后OME(p = 0.34)方面没有差异。

结论

与全身镇痛相比,FICB使早期手术患者在术前评估时疼痛评分得到改善,而仅当手术时间距入院超过24小时时,FICB才会在术前减少阿片类药物的消耗。

证据级别

II,前瞻性,治疗性。

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