Tanner Ii Allen, Jarvis Stephanie, Orlando Alessandro, Nwafo Nnamdi, Madayag Robert, Roberts Zachary, Corrigan Chad, Carrick Matthew, Bourg Pamela, Smith Wade, Bar-Or David
Penrose Hospital, 2222 North Nevada Ave, Colorado Springs, CO, 80907, USA.
ION Research, 383 Corona St. #319, Denver, CO, 80218, USA.
J Clin Orthop Trauma. 2020 Feb;11(Suppl 1):S56-S61. doi: 10.1016/j.jcot.2019.12.001. Epub 2019 Dec 6.
There are multiple reports on the effect of time to surgery for geriatric hip fractures; it remains unclear if earlier intervention is associated with improved mortality, hospital length of stay (HLOS), or cost.
This was a multi-center retrospective cohort study. Patients (≥65y.) admitted (1/14-1/16) to six level 1 trauma centers for isolated hip fractures were included. Patients were dichotomized into early (≤24 h of admission) or delayed surgery (>24 h). The primary outcome was mortality using the CDC National Death Index. Secondary outcomes included HLOS, complications, and hospital cost.
There were 1346 patients, 467 (35%) delayed and 879 (65%) early. The early group had more females (70% vs. 61%, p < 0.001) than the delayed group. The delayed group had a median of 2 comorbidities, whereas the early group had 1, p < 0.001. Mortality and complications were not significantly different between groups. After adjustment, the delayed group had no statistically significant increased risk of dying within one year, OR: 1.1 (95% CI:0.8, 1.5), compared to the early group. The average difference in HLOS was 1.1 days longer for the delayed group, when compared to the early group, p-diff<0.001, after adjustment. The average difference in cost for the delayed group was $2450 ($1550, $3400) more expensive per patient, than the early group, p < 0.001.
The results of this study provide further evidence that surgery within 24 h of admission is not associated with lower odds of death when compared to surgery after 24 h of admission, even after adjustment. However, a significant decrease in cost and HLOS was observed for early surgery. If causally linked, our data are 95% confident that earlier treatment could have saved a maximum of $1,587,800. Early surgery should not be pursued purely for the motivation of reducing hospital costs.
Level III.
关于老年髋部骨折手术时机的影响已有多篇报道;早期干预是否与死亡率降低、住院时间(HLOS)缩短或成本降低相关仍不清楚。
这是一项多中心回顾性队列研究。纳入了(1/14 - 1/16)因单纯髋部骨折入住六个一级创伤中心的患者(≥65岁)。患者被分为早期手术组(入院后≤24小时)或延迟手术组(>24小时)。主要结局是使用疾病预防控制中心国家死亡指数的死亡率。次要结局包括住院时间、并发症和住院费用。
共有1346例患者,467例(35%)延迟手术,879例(65%)早期手术。早期手术组女性比例高于延迟手术组(70%对61%,p < 0.001)。延迟手术组的合并症中位数为2种,而早期手术组为1种,p < 0.001。两组之间的死亡率和并发症无显著差异。调整后,与早期手术组相比,延迟手术组在一年内死亡风险无统计学显著增加,OR:1.1(95%CI:0.8,1.5)。调整后,延迟手术组的平均住院时间比早期手术组长1.1天,p - diff < 0.001。延迟手术组的平均费用比早期手术组每位患者贵2450美元(1550美元,3400美元),p < 0.001。
本研究结果进一步证明,即使在调整后,与入院24小时后手术相比,入院24小时内手术与较低的死亡几率无关。然而,早期手术可显著降低成本和缩短住院时间。如果存在因果关系,我们的数据有95%的把握认为早期治疗最多可节省1587800美元。不应仅仅为了降低医院成本而进行早期手术。
三级。