Sasahara Hiroka, Yatsu Shoichiro, Wada Hideki, Sai Eiryu, Moriya Soshi, Miyazaki Suguru, Kajimoto Kan, Ogita Manabu, Suwa Satoru
Department of Cardiovascular Medicine, Juntendo University Shizuoka Hospital, Izunokuni-shi, Japan.
Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Case Rep Cardiol. 2022 Nov 11;2022:6025354. doi: 10.1155/2022/6025354. eCollection 2022.
Although cardiac metastasis of malignant tumors has often been reported, undifferentiated uterine sarcoma (UUS) is a rare and aggressive uterine tumor. Thus, little is known of the UUS as a primary site of cardiac metastasis. We report a case of a 66-year-old woman, with a history of uterine myoma for 30 years, who was hospitalized with a large uterine tumor and cardiac masses. Although we investigated cardiac masses using imaging modalities, such as ultrasound, cardiac computer tomography, and magnetic resonance imaging, it was challenging to determine the masses as metastasis or thrombi. Cardiac masses were removed by surgery to assess the tissue characteristics and were later identified as tumors due to their appearance. Then, pathological findings revealed that UUS spreads to the right ventricle. We attempted chemotherapy after surgery; however, the disease progressed very quickly and the patient died on the 49th day of admission. In this report, we described the case of a patient with a difficult diagnosis and rapid disease progression of cardiac metastasis from UUS.
尽管恶性肿瘤的心脏转移经常被报道，但未分化子宫肉瘤（UUS）是一种罕见且侵袭性强的子宫肿瘤。因此，关于UUS作为心脏转移的原发部位知之甚少。我们报告一例66岁女性病例，该患者有30年子宫肌瘤病史，因巨大子宫肿瘤和心脏肿物入院。尽管我们使用超声、心脏计算机断层扫描和磁共振成像等影像学手段对心脏肿物进行了检查，但很难确定这些肿物是转移瘤还是血栓。通过手术切除心脏肿物以评估组织特征，后来根据其外观确定为肿瘤。随后，病理检查结果显示UUS已扩散至右心室。术后我们尝试进行化疗；然而，疾病进展非常迅速，患者在入院第49天死亡。在本报告中，我们描述了一例诊断困难且疾病进展迅速的UUS心脏转移患者的病例。
