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On the mechanisms underlying activation and reversal of high altitude-induced pulmonary hypertension in humans - Another piece in the pulmonary puzzle.

作者信息

Berger Marc Moritz, Bailey Damian Miles

机构信息

Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.

出版信息

Exp Physiol. 2023 Jan;108(1):1-4. doi: 10.1113/EP090967. Epub 2022 Nov 21.

DOI:10.1113/EP090967
PMID:36409273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10103756/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82ee/10103756/2cb7e7239236/EPH-108-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82ee/10103756/2cb7e7239236/EPH-108-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82ee/10103756/2cb7e7239236/EPH-108-1-g001.jpg

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本文引用的文献

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Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude.在逐渐攀登至高海拔的过程中,夏尔巴人和低地居民对补充氧气的肺血管反应性。
Exp Physiol. 2023 Jan;108(1):111-122. doi: 10.1113/EP090458. Epub 2022 Nov 20.
2
Sensors and signals: the role of reactive oxygen species in hypoxic pulmonary vasoconstriction.传感器和信号:活性氧在低氧性肺血管收缩中的作用。
J Physiol. 2019 Feb;597(4):1033-1043. doi: 10.1113/JP275852. Epub 2018 Aug 28.
3
Redox-regulation of haemostasis in hypoxic exercising humans: a randomised double-blind placebo-controlled antioxidant study.
低氧运动人群止血的氧化还原调节:一项随机、双盲、安慰剂对照抗氧化研究。
J Physiol. 2018 Oct;596(20):4879-4891. doi: 10.1113/JP276414. Epub 2018 Aug 29.
4
Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5300 m).在逐步攀登至高海拔(5300米)过程中急性肺血管对低氧反应性的变化。
Exp Physiol. 2017 Jun 1;102(6):711-724. doi: 10.1113/EP086083. Epub 2017 May 21.
5
Effect of Increased Blood Flow on Pulmonary Circulation Before and During High Altitude Acclimatization.高海拔适应前及适应过程中血流增加对肺循环的影响。
High Alt Med Biol. 2016 Dec;17(4):305-314. doi: 10.1089/ham.2016.0004. Epub 2016 Oct 18.
6
Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.缺氧性肺血管收缩:从分子机制到医学应用
Chest. 2017 Jan;151(1):181-192. doi: 10.1016/j.chest.2016.09.001. Epub 2016 Sep 16.
7
Modulation of the Hypoxic Response.缺氧反应的调节
Adv Exp Med Biol. 2016;903:259-71. doi: 10.1007/978-1-4899-7678-9_18.
8
Reactive oxygen species in pulmonary vascular remodeling.肺血管重构中的活性氧。
Compr Physiol. 2013 Jul;3(3):1011-34. doi: 10.1002/cphy.c120024.
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