Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.
Department of Physical Therapy and Rehabilitation, Çankırı Karatekin University, Çankırı, Turkey.
Neurol Res. 2023 May;45(5):407-414. doi: 10.1080/01616412.2022.2149510. Epub 2022 Nov 22.
The aim of the study was to evaluate the effects of freezing of gait (FOG) on static and dynamic balance.
Twenty patients with Parkinson's disease with and without FOG [PD+FOG (68,6±6,39 years) and PD-FOG group (70,6±4,57 years)] and 10 healthy individuals (68,4±4,92 years) with similar demographic characteristics were included in the study. Balance was compared between the three groups. Balance was evaluated with clinical tests Limits of stability (LoS) and body sway were measured using the E-LINK FP3 Force Plate and the Korebalance Balance Evaluation System, which measure the balance in static and dynamic conditions. Center of pressure (COP) change and average sway velocity were evaluated with the Zebris RehaWalk system.
Total and subscale scores of the Unified Parkinson's Disease Rating Scale were significantly higher in the PD+FOG group (p<0.05). The balance test results for both groups were similar (p>0.05). The PD+FOG group performed worse on the computerized static balance tests, the COP analysis, and the dynamic balance total score than the other two groups (p<0.05). The PD+FOG group had significantly greater sustained weight deviation than the healthy controls (p<0.05). Patients with Parkinson's disease had a lower LoS in the posterior direction than healthy controls (p<0.05).
FOG affects the dynamic balance more negatively than the static balance. In addition, FOG reduces LoS in the posterior direction and increases body sway in the anterior-posterior direction, which can lead to falls.
本研究旨在评估冻结步态（FOG）对静态和动态平衡的影响。
本研究纳入了 20 名伴或不伴 FOG 的帕金森病患者[PD+FOG 组（68.6±6.39 岁）和 PD-FOG 组（70.6±4.57 岁）]和 10 名具有相似人口统计学特征的健康个体，比较了三组之间的平衡情况。通过临床测试评估平衡，使用 E-LINK FP3 力板和 Korebalance 平衡评估系统测量静态和动态条件下的平衡，分别测量稳定性极限（LoS）和身体摆动；使用 Zebris RehaWalk 系统评估中心压力（COP）变化和平均摆动速度。
PD+FOG 组的统一帕金森病评定量表总分和各分量表评分均显著高于其他两组（p<0.05）。但两组的平衡测试结果无显著差异（p>0.05）。与其他两组相比，PD+FOG 组在计算机静态平衡测试、COP 分析和动态平衡总分方面表现更差（p<0.05）。与健康对照组相比，PD+FOG 组的持续体重偏差显著更大（p<0.05）。帕金森病患者的后向 LoS 显著低于健康对照组（p<0.05）。
FOG 对动态平衡的影响比静态平衡更严重。此外，FOG 降低了后向 LoS，并增加了前-后向的身体摆动，这可能导致跌倒。
