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ST 段抬高型急性心肌梗死无复流现象的预测因素。

Predictors in no-reflow phenomenon in acute myocardial infarction with ST-segment elevation.

机构信息

Departamento de Cardiología, Centro Médico Nacional del Noroeste, IMSS.

Departamento de Ciencias de la Salud, Universidad de Sonora. Ciudad Obregón, Sonora, México.

出版信息

Arch Cardiol Mex. 2022;92(4):461-468. doi: 10.24875/ACM.21000346.

DOI:10.24875/ACM.21000346
PMID:36413699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9681523/
Abstract

BACKGROUND

No-reflow (NR) phenomenon is one of the most feared complications after percutaneous coronary intervention (PCI) in the treatment of ST-segment elevation myocardial infarction (STEMI) due to its high morbidity and mortality.

OBJECTIVE

To describe the predictive factors for NR phenomenon in a group of subjects with STEMI treated with PCI.

METHOD

One hundred and three cases of STEMI who underwent PCI. The subjects were divided according to the presence of NR phenomenon. In a multivariate analysis age, gender, comorbidities, weight, and other clinical and laboratory parameters were studied as predictors of NR phenomenon were studied.

RESULTS

In this study, logistic regression analysis identified as independent factors for the development of NR phenomenon baseline TIMI flow ≤ 2 (OR 6.03; 95% CI, 0.9 to 11.8; p = 0.04), ER KDIGO ≥ 3 (OR OR 2.61; 95% CI, 1.0 to 2.4; p = 0.04).

CONCLUSIONS

NR phenomenon continues to be a challenge for short and long-term morbidity and mortality in STEMI. The identified factors can be used for the stratification of cases with STEMI and risk of NR phenomenon prior to PCI.

摘要

背景

无复流(NR)现象是经皮冠状动脉介入治疗(PCI)治疗 ST 段抬高型心肌梗死(STEMI)后最可怕的并发症之一,其发病率和死亡率都很高。

目的

描述一组接受 PCI 治疗的 STEMI 患者 NR 现象的预测因素。

方法

103 例 STEMI 患者接受 PCI。根据是否存在 NR 现象对患者进行分组。在多变量分析中,研究了年龄、性别、合并症、体重和其他临床及实验室参数作为 NR 现象预测因素。

结果

在这项研究中,逻辑回归分析确定基线 TIMI 血流≤2(OR 6.03;95%CI,0.9 至 11.8;p=0.04)、ER KDIGO≥3(OR 2.61;95%CI,1.0 至 2.4;p=0.04)是 NR 现象发展的独立因素。

结论

NR 现象仍然是 STEMI 患者短期和长期发病率和死亡率的挑战。确定的因素可用于 STEMI 病例的分层和 PCI 前 NR 现象的风险分层。

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