Yang Li, Cong Hongliang, Lu Yali, Huo Xingyu, Chen Juan
Department of Cardiology, Chest Hospital Tianjin University, Tianjin, China.
Department of Epidemiology and Health Statistics, School of Public Health, Tianjin Medical University, Tianjin, China.
J Thorac Dis. 2025 Aug 31;17(8):5760-5776. doi: 10.21037/jtd-2025-39. Epub 2025 Aug 28.
Insufficient blood flow following percutaneous coronary intervention (PCI) presents a significant challenge in the management of ST-segment elevation myocardial infarction (STEMI). This study aims to provide a bibliometric analysis of the research landscape pertaining to the no-reflow phenomenon in STEMI patients who have undergone PCI.
A systematic literature search was conducted on the absence of blood flow following STEMI PCI utilizing the Web of Science Core Collection database, covering the period from 2000 to 2025. Bibliometric indicators, co-occurrence analysis, and burst detection were employed through the use of VOSviewer, CiteSpace, and R-bibliometrix tools.
The analysis included 1,101 publications authored by contributors from 60 countries and 1,811 institutions. China led in research output, contributing 255 articles, while Heart Center Leipzig GmbH was the most prolific institution. Thiele H, with an H-index of 26, emerged as the most influential author. Journals such as the and the served as key platforms for this research. Keyword analysis revealed a shift in research trends, from early disease- and technique-related terms such as "thrombus", "aspiration" and "thrombolytic therapy" to recent terms focused on precision medicine, including "enhancement" and "quantification".
This study comprehensively elucidated global collaboration patterns and the dynamic evolution of research trends in this research field. Keyword analysis revealed a shift in focus from conventional techniques to patient-centered care and personalized treatment strategies in precision medicine. These insights provided valuable guidance for researchers.
经皮冠状动脉介入治疗（PCI）后血流不足是ST段抬高型心肌梗死（STEMI）管理中的一项重大挑战。本研究旨在对接受PCI的STEMI患者无复流现象的研究领域进行文献计量分析。
利用科学网核心合集数据库对STEMI PCI后血流缺失情况进行系统的文献检索，涵盖2000年至2025年期间。通过使用VOSviewer、CiteSpace和R-bibliometrix工具进行文献计量指标、共现分析和突发检测。
分析包括来自60个国家和1811个机构的贡献者撰写的1101篇出版物。中国在研究产出方面领先，贡献了255篇文章，而莱比锡心脏中心有限公司是产出最多的机构。H指数为26的蒂勒·H成为最具影响力的作者。《 》和《 》等期刊是该研究的关键平台。关键词分析显示研究趋势发生了转变，从早期与疾病和技术相关的术语，如“血栓”、“抽吸”和“溶栓治疗”，转向了近期专注于精准医学的术语，包括“增强”和“量化”。
本研究全面阐明了该研究领域的全球合作模式和研究趋势的动态演变。关键词分析显示重点从传统技术转向了精准医学中以患者为中心的护理和个性化治疗策略。这些见解为研究人员提供了有价值的指导。
