Hematology and Oncology, Henry Ford Health System, Detroit, Michigan, USA
Internal Medicine, Ascension St John Hospital, Detroit, Michigan, USA.
BMJ Case Rep. 2022 Nov 22;15(11):e252423. doi: 10.1136/bcr-2022-252423.
Hairy cell leukaemia (HCL) is a rare B cell malignancy that is associated with the BRAF V600E mutation and has good treatment response to purine analogues. Its presentation synchronously with other malignancies has been rarely reported. Here, we present a patient with HCL with hepatic involvement who was also found to have pancreatic adenocarcinoma concomitantly at the time of diagnosis. Treating these rare cases simultaneously is a challenge clinically. Throughout this case study, we provide our approach on how oncological care teams provided care for this complicated and rare disease state.
毛细胞白血病（HCL）是一种罕见的 B 细胞恶性肿瘤，与 BRAF V600E 突变相关，对嘌呤类似物治疗反应良好。其与其他恶性肿瘤同时发生的表现很少有报道。在这里，我们报告了一例伴有肝受累的 HCL 患者，在诊断时还同时发现患有胰腺腺癌。同时治疗这些罕见病例在临床上是一个挑战。在整个病例研究中，我们提供了肿瘤护理团队如何为这种复杂和罕见的疾病状态提供护理的方法。
