Dhanesar Gurneel K, Livingston Jonathan, Maroules Michael, Lee Sheue H
Internal Medicine, New York Medical College at St. Mary's General Hospital, Passaic and St. Clare's Health, Denville, USA.
Hematology and Oncology, St. Mary's General Hospital, Passaic, USA.
Cureus. 2023 Jun 1;15(6):e39830. doi: 10.7759/cureus.39830. eCollection 2023 Jun.
Hairy cell leukemia (HCL) is a rare neoplasm of the B-cell lineage that is characterized by an indolent course and infiltration of the spleen, the bone marrow, and the reticuloendothelial system. Splenectomy is considered an effective treatment for peripheral cytopenia in patients with HCL. Hepatic involvement of hairy cells with infiltration of the sinusoidal endothelial cells is rarely reported in the literature and is not well understood. We present the case of an 88-year-old male with a history of traumatic splenectomy who was found to have a relapse of classic hairy cell leukemia within the hepatic portal system.
毛细胞白血病（HCL）是一种罕见的B细胞系肿瘤，其特征为病程进展缓慢，并浸润脾脏、骨髓和网状内皮系统。脾切除术被认为是治疗HCL患者外周血细胞减少的有效方法。毛细胞累及肝脏并浸润窦状内皮细胞的情况在文献中鲜有报道，目前对此了解也不多。我们报告了一例88岁男性患者，该患者有外伤性脾切除病史，被发现肝门系统内经典型毛细胞白血病复发。
