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比较“临床直觉”与临床决策支持系统(PERC 规则、Wells 评分、修订版日内瓦评分和 YEARS 标准)在急性肺栓塞诊断中的应用。

Comparing 'clinical hunch' against clinical decision support systems (PERC rule, wells score, revised Geneva score and YEARS criteria) in the diagnosis of acute pulmonary embolism.

机构信息

Department of Physiology and Pharmacology, Karolinska Institutet, 171 77, Stockholm, Sweden.

Department of Imaging and Physiology, Cardiothoracic Section, Karolinska University Hospital, 171 76, Stockholm, Sweden.

出版信息

BMC Pulm Med. 2022 Nov 21;22(1):432. doi: 10.1186/s12890-022-02242-1.

Abstract

BACKGROUND

Pulmonary embolism (PE) is a common and potentially life-threatening condition. Since it is considered a 'do not miss' diagnosis, PE tends to be over-investigated beyond the evidence-based clinical decision support systems (CDSS), which in turn subjects patients to unnecessary radiation and contrast agent exposure with no apparent benefits in terms of outcome. The purpose of this study was to evaluate the yield of 'clinical hunch' (gestalt) and four CDSS: the PERC Rule, Wells score, revised Geneva score, and Years criteria.

METHODS

A review was conducted on the Electronic Medical Records (EMR) of 1566 patients from the Emergency Department at a tertiary teaching hospital who underwent CTPA from the 1st of January 2018 to the 31st of December 2019. The scores for the four CDSS were calculated retrospectively from the EMR data. We considered that a CTPA had been ordered on a clinical hunch when there was no mention of CDSS in the EMR, and no D-dimer test. A bypass of CDSS was confirmed when any step of the diagnostic algorithms was not followed.

RESULTS

Of the total 1566 patients who underwent CTPA, 265 (17%) were positive for PE. The diagnosis yield from the five decision groups (clinical hunch and four CDSS) was as follows-clinical hunch, 15%; PERC rule, 18% (6% when bypassed); Wells score, 19% (11% when bypassed); revised Geneva score, 26% (13% when bypassed); and YEARS criteria, 18% (6% when bypassed).

CONCLUSION

Clinicians should trust the evidence-based clinical decision support systems in line with the international guidelines to diagnose PE.

摘要

背景

肺栓塞(PE)是一种常见且可能危及生命的病症。由于其被认为是“不容错过”的诊断,因此在基于证据的临床决策支持系统(CDSS)之外,PE 的检查往往过度,这反过来又使患者受到不必要的辐射和造影剂暴露,而在结果方面没有明显的获益。本研究旨在评估“临床直觉”(整体观)和四个 CDSS 的检出率:PERC 规则、Wells 评分、修订的日内瓦评分和 YEARS 标准。

方法

对一家三级教学医院急诊科的 1566 名患者的电子病历(EMR)进行了回顾性研究,这些患者于 2018 年 1 月 1 日至 2019 年 12 月 31 日期间接受了 CTPA。从 EMR 数据中回顾性计算了四个 CDSS 的评分。当 EMR 中未提及 CDSS 且未进行 D-二聚体检测时,我们认为 CTPA 是基于临床直觉进行的。当未遵循诊断算法的任何步骤时,可确认绕过 CDSS。

结果

在接受 CTPA 的 1566 名患者中,265 名(17%)患者的 CTPA 结果呈阳性。五个决策组(临床直觉和四个 CDSS)的诊断检出率如下-临床直觉,15%;PERC 规则,18%(绕过时为 6%);Wells 评分,19%(绕过时为 11%);修订的日内瓦评分,26%(绕过时为 13%);YEARS 标准,18%(绕过时为 6%)。

结论

临床医生应根据国际指南信任基于证据的临床决策支持系统,以诊断 PE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537f/9682736/90f727c3bb3d/12890_2022_2242_Fig1_HTML.jpg

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