Zhang Han, Qin Liyun, Jin Caiping, Ju Huidong, Jiang Ruiping, Li Lijie, Zhang Hong, Gao Weili, Wei Xiuping, Dong Hongyan, Lu Fei, Lv Guoping
Basic Medicine College, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang 050011, China.
Pathogens. 2022 Nov 11;11(11):1333. doi: 10.3390/pathogens11111333.
is a common opportunistic and zoonotic pathogen in the world and could easily cause human infections and food contaminations. This study investigated the sequence typing and resistance profiles of isolates from patient and food samples in Shijiazhuang, China. A total of 101 isolates were distributed into six clonal complexes (CCs) and 16 singletons. A total of 86 patient isolates were distributed into six clonal CCs and 12 singletons, including a new ST. CC59, CC5, CC22, and CC398 were the predominant CCs of patient isolates. A total of 15 foodborne isolates were distributed into 3 CCs and 4 STs, and CC1 was the most prevalent CC. Moreover, 101 isolates had high resistance to penicillin and low resistance to chloramphenicol and rifampicin. A total of 39 strains of methicillin-resistant (MRSA) were detected in this study, including thirty-eight strains of patient isolates (44.2%, 38/86) and one strain of food isolates (6.7%, 1/15). MRSA-ST5, MRSA-ST59, and MRSA-ST239 were the predominant MRSA isolates in hospitals. The present study explained the relationship between isolated from patient and food samples and indicated the risks of in infectious diseases.
是世界上一种常见的机会性和人畜共患病原体，很容易导致人类感染和食品污染。本研究调查了中国石家庄患者和食品样本中分离株的序列分型和耐药谱。总共101株分离株被分为6个克隆复合体（CCs）和16个单株。总共86株患者分离株被分为6个克隆CCs和12个单株，包括一个新的ST型。CC59、CC5、CC22和CC398是患者分离株的主要CCs。总共15株食源性分离株被分为3个CCs和4个ST型，CC1是最常见的CC。此外，101株分离株对青霉素耐药性高，对氯霉素和利福平耐药性低。本研究共检测到39株耐甲氧西林金黄色葡萄球菌（MRSA），其中患者分离株38株（44.2%，38/86），食品分离株1株（6.7%，1/15）。MRSA-ST5、MRSA-ST59和MRSA-ST239是医院中主要的MRSA分离株。本研究解释了患者和食品样本中分离的金黄色葡萄球菌之间的关系，并指出了金黄色葡萄球菌在传染病中的风险。
