Clyde Alexis, Bismar Danna, Agnew Gabrielle, Kuper Laura E
Children's Health System of Texas, 1935 Medical District Dr., Mail Code CH 12.01, Dallas, TX, 75235, USA.
University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Autism Dev Disord. 2024 Feb;54(2):615-627. doi: 10.1007/s10803-022-05814-6. Epub 2022 Nov 24.
Autism spectrum disorder (ASD) and ASD symptoms are overrepresented among gender-diverse youth across studies. Gender-diverse and ASD youth are at risk for anxiety, but anxiety is unclear among gender-diverse youth with ASD. The Social Communication Questionnaire (SCQ) is a commonly used ASD screener, including in multidisciplinary gender-affirming programs, but scholars have disagreed on the most optimal cut-off score. To date, no study has investigated the sensitivity and specificity of its established cut-off score of 15 with a sample of transgender youth. Gaining more accurate information about the utility of ASD screening tools with gender diverse youth is critical in order to help refer youth to needed services. Among a sample of 325 transgender youth, this study sought to determine an optimal cut-off score for the SCQ, the prevalence of ASD and ASD symptoms, and the relationship between ASD and anxiety within this population. The current study found that a lower cut-off score of 11 yielded optimal sensitivity and specificity (i.e., the best balance of accurately identifying individuals with ASD based on the screener), and analyses found an overrepresentation of ASD (5.2%) and ASD traits (12.1%). Transgender youth with ASD or ASD symptoms had higher anxiety, and all youth perceived themselves as more anxious than their parents. Future research is needed to identify the needs of this population, with particular consideration for the lived experiences of gender diverse and transgender youth.
在各项研究中,自闭症谱系障碍(ASD)及ASD症状在性别多元化青少年中普遍存在。性别多元化青少年和患有ASD的青少年都有焦虑风险,但患有ASD的性别多元化青少年的焦虑情况尚不清楚。社交沟通问卷(SCQ)是一种常用的ASD筛查工具,多学科性别肯定项目中也会使用,但学者们对于最适宜的临界分数存在分歧。迄今为止,尚无研究以跨性别青少年样本调查其既定临界分数15的敏感性和特异性。获取关于ASD筛查工具在性别多元化青少年中效用的更准确信息,对于帮助将青少年转介至所需服务至关重要。在325名跨性别青少年样本中,本研究旨在确定SCQ的最佳临界分数、ASD及ASD症状的患病率,以及该人群中ASD与焦虑之间的关系。当前研究发现,较低的临界分数11产生了最佳的敏感性和特异性(即基于筛查工具准确识别患有ASD个体的最佳平衡),分析发现ASD(5.2%)和ASD特征(12.1%)的比例过高。患有ASD或ASD症状的跨性别青少年焦虑程度更高,且所有青少年都认为自己比父母更焦虑。需要未来的研究来确定这一人群的需求,尤其要考虑性别多元化和跨性别青少年的生活经历。