Saheban Maleki Mohsen, Khedri Behzad, Ebrahimpour Roodposhti Maryam, Askari Majdabadi Hesamedin, Seyedrezaei Seyedeh Omolbanin, Amanat Nasir, Poursadeqiyan Mohsen, Khajehnasiri Farahnaz, Amiri Roya
Department of Anesthesia, Clinical Research Developmental Unit Bohlool Hospital, Gonabad University of Medical Science, Gonabad, Iran.
Department of Social Work, Social Studies Faculty, Hanze University of Applied Science, Groningen, Netherlands.
Arch Acad Emerg Med. 2022 Oct 6;10(1):e80. doi: 10.22037/aaem.v10i1.1720. eCollection 2022.
Understanding the epidemiology of traumatic spinal cord injuries (TSCIs) can be helpful for policymakers and planners to consider appropriate strategies to control and prevent these injuries. This study aimed to determine the epidemiological characteristics of TSCI in Iran in order to increase knowledge and awareness of these injuries.
A systematic literature search was conducted up to January 2022 in the electronic databases, including PubMed, Scopus, Web of Science, Google Scholar, SID, Iranmedex, and Magiran. The quality of included studies was evaluated using the STORBE checklist. Comprehensive meta-analysis was used to analyze the data.
Nineteen studies involving 9416 cases were included in the study. Participants' pooled mean age was 35.80 ± 1.07 years (95% CI: 33.69 to 37.91), of whom 69% (95% CI: 68% to 70%; <0.05) were male. The most frequent TSCI occurred in the age group of less than 30 years. Motor vehicle collisions (MVCs) was the most common cause of TSCI (57%; 95% CI: 25% to 63%), followed by falls (32%; 95% CI: 26% to 38%). Most participants had thoracolumbar (27%; 95% CI: 10% to 55%) and cervical injuries (23%; 95% CI: 16% to 31%), respectively. The incidence of TSCI was estimated at 10.5 per million people. The prevalence of TSCI was 3 per 10000 people. The mortality rate due to TSCI was 3.9% (95% CI: 0.02 to 0.06; <0.05).
Based on the findings of this meta-analysis, the pooled incidence and prevalence of TSCI in the Iranian population were 10.5/1000.000 people and 4.4/10.000 people, respectively. TSCIs had occurred more frequently in males following MVCs, and in the age group under 30 years. The pooled mortality rate due to TSCI was 3.9% (95% CI: 0.02 to 0.06; P<0.05).
了解创伤性脊髓损伤（TSCI）的流行病学情况有助于政策制定者和规划者考虑采取适当策略来控制和预防这些损伤。本研究旨在确定伊朗TSCI的流行病学特征，以增进对这些损伤的认识。
截至2022年1月，在电子数据库中进行了系统的文献检索，这些数据库包括PubMed、Scopus、Web of Science、谷歌学术、SID、Iranmedex和Magiran。使用STORBE清单评估纳入研究的质量。采用综合荟萃分析来分析数据。
该研究纳入了19项涉及9416例病例的研究。参与者的合并平均年龄为35.80±1.07岁（95%置信区间：33.69至37.91），其中69%（95%置信区间：68%至70%；<0.05）为男性。最常见的TSCI发生在年龄小于30岁的人群中。机动车碰撞（MVC）是TSCI最常见的原因（57%；95%置信区间：25%至63%），其次是跌倒（32%；95%置信区间：26%至38%）。大多数参与者分别有胸腰椎损伤（27%；95%置信区间：10%至55%）和颈椎损伤（23%；95%置信区间：16%至31%）。TSCI的发病率估计为每百万人10.5例。TSCI的患病率为每万人3例。TSCI导致的死亡率为3.9%（95%置信区间：0.02至0.06；<0.05）。
基于该荟萃分析的结果，伊朗人群中TSCI的合并发病率和患病率分别为每百万人10.5例和每万人4.4例。TSCI在男性中因机动车碰撞更为常见，且在30岁以下年龄组中更为频发。TSCI导致的合并死亡率为3.9%（95%置信区间：0.02至0.06；P<0.05）。
