Taylor C R
Oncology. 1978;35(5):187-97.
Immunoperoxidase methods permit the demonstration of a variety of antigens in routinely processed tissues. The morphological detail obtained by this procedure is comparable to orthodox haematoxylin and eosin stained sections, and so offers the diagnostic pathologist the opportunity of simultaneously identifying normal and neoplastic cells both by their morphological characteristics and by their antigenic constitution. The application of this method to a study of maligant lymphomas has contributed to current re-appraisal of classification criteria for this group of neoplasms. It is anticipated that, as specific antisera against a range of different tissue antigens become available, immunoperoxidase methods will have a similar impact upon the re-definition of morphologic criteria related to other neoplasms.
免疫过氧化物酶方法能够在常规处理的组织中显示多种抗原。通过该方法获得的形态学细节与传统苏木精和伊红染色切片相当，因此为诊断病理学家提供了同时根据正常细胞和肿瘤细胞的形态特征及其抗原组成来识别它们的机会。将该方法应用于恶性淋巴瘤的研究有助于对这组肿瘤的分类标准进行当前的重新评估。预计随着针对一系列不同组织抗原的特异性抗血清的出现，免疫过氧化物酶方法将对与其他肿瘤相关的形态学标准的重新定义产生类似的影响。
