Key Laboratory of Cognition and Personality, Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, 400715, China.
School of Psychology, Central China Normal University, Wuhan, 430079, China.
Behav Brain Res. 2023 Feb 15;439:114227. doi: 10.1016/j.bbr.2022.114227. Epub 2022 Nov 24.
Interoceptive sensibility refers to the tendency to focus on internal bodily states and the capacity to detect them. As the subjective dimension of interoception, interoceptive sensibility plays a key role in individuals' health. Self-objectification, a process by which individuals tend to adopt a third-person's perspective of their physical self, leads to decreased interoceptive sensibility. However, few studies regarding the neural basis of interoceptive sensibility and the underlying mechanism of the relationship between self-objectification and interoceptive sensibility have been conducted. In this study, we assessed the resting-state brain activity (fractional amplitude of low-frequency fluctuation, fALFF) and connectivity (resting-state functional connectivity, RSFC) of 442 college students. Whole-brain correlation analyses revealed that a higher level of interoceptive sensibility was linked to higher fALFF in the right inferior frontal gyrus (IFG) and left cerebellum and to lower fALFF in the left paracentral lobule and left superior/middle temporal gyrus. Interoceptive sensibility also was negatively associated with the RSFC between the right IFG and the right secondary somatosensory cortex (S2) and the right IFG and the ventral premotor cortex (VPC). These brain regions and connections are mainly responsible for switching attention to internal/external information and processing body-related somatosensory as well as sensory information. Mediation analyses suggested that the fALFF of the right IFG and the RSFC of IFG-S2 and IFG-VPC mediated the relationship between self-objectification and interoceptive sensibility. Overall, these results suggest that the IFG may be the neural marker of interoceptive sensibility and reveal several potential mediation models of the relationship between brain neural correlates and self-objectification and interoceptive sensibility.
内感受敏感性是指关注内部身体状态和检测这些状态的能力。作为内感受的主观维度，内感受敏感性在个体健康中起着关键作用。自我客观化是指个体倾向于采用第三人称视角看待自己的身体，这导致内感受敏感性降低。然而，关于内感受敏感性的神经基础以及自我客观化和内感受敏感性之间关系的潜在机制的研究较少。在这项研究中，我们评估了 442 名大学生的静息态脑活动（低频振幅分数，fALFF）和连接（静息态功能连接，RSFC）。全脑相关分析显示，较高的内感受敏感性与右侧下额回（IFG）和左侧小脑的 fALFF 较高以及左侧旁中央小叶和左侧上/中颞回的 fALFF 较低有关。内感受敏感性还与右侧 IFG 与右侧次级体感皮层（S2）和右侧 IFG 与腹侧运动前皮层（VPC）之间的 RSFC 呈负相关。这些大脑区域和连接主要负责将注意力从内部/外部信息切换到处理与身体相关的躯体感觉和感觉信息。中介分析表明，右侧 IFG 的 fALFF 和 IFG-S2 和 IFG-VPC 的 RSFC 介导了自我客观化和内感受敏感性之间的关系。总的来说，这些结果表明 IFG 可能是内感受敏感性的神经标志物，并揭示了大脑神经相关物与自我客观化和内感受敏感性之间关系的几个潜在中介模型。
