Sunuwar Neela, Jaishi Prakash Poudel, Twayana Anu Radha, Neupane Prabhat Kiran, Neupane Sandhya Kiran
BP Koirala Institute of Health Sciences, School of Public Health and Community Medicine, Nepal.
Nepalese Army Institute of Health Sciences College of Medicine, Nepal.
Ann Med Surg (Lond). 2022 Dec;84:104880. doi: 10.1016/j.amsu.2022.104880. Epub 2022 Nov 19.
SARS-CoV, MERS-CoV, and SARS-CoV-2, later named coronavirus disease 2019 (COVID-19), are three highly pathogenic and lethal human coronaviruses that have arisen in the last two decades. Pregnant women have a higher risk due to a special state of immunosuppression. However, there is no proof that pregnant women and their babies are more vulnerable to infection, as data is limited.The primary goal of this retrospective study is to examine the effects of early COVID-19 diagnosis and to address the best method of delivery based on medical records of neonatal and maternal outcomes observed at Nepal's Paropakar Maternity Hospital. This retrospective research will determine whether vaginal delivery is healthy compared to cesarean delivery and whether the outcome of a COVID-19 pregnancy in both mother and the baby is independent of the disease's status of the mother.
Study design: The proposed study is a retrospective cross-sectional study.
104 cases of COVID positive pregnancy with vaginal delivery or caesarean section.
The neonatal outcomes of COVID pregnancy revealed at least 51% baby born with Low APGAR score, 18% born prematurely, 19% with low birth weight, 7% requiring NICU admission, 3% Neonatal asphyxia, and 2% Neonatal death. Furthermore, when normal vaginal delivery and Cesarean section were compared there was no significant between the differences found in the outcomes.
The COVID positive status had no association with the perinatal outcomes. Moreover, COVID status rarely affected the course of pregnancy.
STROCSS 2021.
严重急性呼吸综合征冠状病毒(SARS-CoV)、中东呼吸综合征冠状病毒(MERS-CoV)以及后来被命名为2019冠状病毒病(COVID-19)的新型冠状病毒,是过去二十年来出现的三种高致病性且致命的人类冠状病毒。孕妇由于处于特殊的免疫抑制状态而面临更高风险。然而,由于数据有限,尚无证据表明孕妇及其胎儿更容易感染。这项回顾性研究的主要目的是根据在尼泊尔帕罗帕卡尔妇产医院观察到的新生儿和产妇结局的病历,研究COVID-19早期诊断的影响,并探讨最佳分娩方式。这项回顾性研究将确定与剖宫产相比,阴道分娩是否健康,以及COVID-19感染孕妇及其婴儿的结局是否与母亲的疾病状况无关。
研究设计:拟进行的研究为回顾性横断面研究。
104例COVID阳性孕妇,采用阴道分娩或剖宫产。
COVID感染孕妇的新生儿结局显示,至少51%的婴儿出生时阿氏评分低,18%早产,19%出生体重低,7%需要入住新生儿重症监护病房(NICU),3%新生儿窒息,2%新生儿死亡。此外,比较正常阴道分娩和剖宫产时,结局差异无统计学意义。
COVID阳性状态与围产期结局无关。此外,COVID状态很少影响妊娠过程。
STROCSS 2021。